MABF33
抗-MHC II类（I-A/I-E）抗体，克隆M5/114
clone M5/114, from rat
别名:
CD74 molecule, major histocompatibility complex, class II invariant chain, Ia-associated invariant chain, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), gamma chain of class II antigens, Ia antigen-
生物来源
rat
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
M5/114, monoclonal
种属反应性
mouse
技术
flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG2bκ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Cd74(16149)
一般描述
MHC II类相关不变量链（I-A/I-E），也称Ia抗原相关不变量链，是含有单个甲状腺球蛋白I型结构域的单通道II型膜糖蛋白。它们是MHC II类抗原处理过程中的关键组成部分，在α / β异二聚体合成后形成稳定复合物，并协调复合物从发生II类肽装载的ER区转移。
观测值〜32 kDa。
选择性剪接产生2种亚型：32 kDa（长亚型）和 24 kDa（短亚型）。
选择性剪接产生2种亚型：32 kDa（长亚型）和 24 kDa（短亚型）。
应用
使用经验证可用于WB、FC、IH的该抗-MHC II类（I-A/I-E）抗体，克隆M5/114检测MHC II类（I-A/I-E）。
流式细胞分析：先前批次已被独立实验室用于脾细胞FC。（Bhattacharya, A., et al. (1981). The Journal of immunology.127(6):2488-2496。）
免疫组织化学分析：先前批次已被独立实验室用于胸腺组织IH。(de Bont, E., et al. (1999). Int. Immunol. 11(8):1295-1306.）
免疫组织化学分析：先前批次已被独立实验室用于胸腺组织IH。(de Bont, E., et al. (1999). Int. Immunol. 11(8):1295-1306.）
外形
形式：纯化
分析说明
已通过蛋白质印迹在小鼠脾组织裂解液中进行了评估。
蛋白质印迹分析：1 µg/mL该抗体在10 µg小鼠脾组织裂解液中检测到MHC II类（I-A/I-E）。
蛋白质印迹分析：1 µg/mL该抗体在10 µg小鼠脾组织裂解液中检测到MHC II类（I-A/I-E）。
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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