生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
CL143, monoclonal
种属反应性
guinea pig, human, mouse, rat
技术
flow cytometry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型
IgGκ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... MX1 (4599)
一般描述
免疫原
应用
免疫组织化学分析:代表性批次使用石蜡包埋的组织切片在患者源性皮肤病变样品中检测到MxA免疫反应性(Urosevic,M.,et al.(2007).J. Clin. Invest. 117(10): 2834–2846; Urosevic, M., et al. (2005).J. Natl.Cancer Inst.97(15):1143-1153)。
流式细胞术分析:一个代表性批次在MxA转染的U-87-H4和U-87-D11中检测到MxA表达,但在未转染的U-87-K4人胶质母细胞瘤细胞中未检测到(Schneider-Schaulies,S.,et al.(1994).J. Virol.68(11):6910-6917)。
蛋白质印迹分析:一个代表性批次在接受重组人α-IFN鼻内给药的豚鼠的肺组织中检测到稳健的MxA诱导(Van Hoeven,N.,et al.(2009).J. Virol.83(7): 2851–2861)。
蛋白质印迹分析:在腹膜内接种汉城病毒后,一个代表性批次在大鼠的肺组织中检测到时间依赖性MxA诱导(Hannah,M.F.,et al.(2008).Brain Behav Immun.22(4):503-516)。
免疫沉淀分析:一个代表性批次免疫沉淀来自表达鼠MxA的Swiss 3T3细胞的MxA(克隆4.5.15)(Flohr,F.,et al.(1999).FEBS Lett.463(1-2):24-28)。
免疫球蛋白 & 免疫学
炎症 & 免疫学
生化/生理作用
外形
制备说明
分析说明
蛋白质印迹分析:0.5 µg/mL该抗体在10 µg Swiss 3T3(克隆4.5.15)细胞裂解物中检测到MxA。
其他说明
免责声明
未找到合适的产品?
试试我们的产品选型工具.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
相关内容
"Mods – modifications – small alterations can have a big impact on form and function. In the motorsports world, stock vehicles are modified to enhance their performance. Modifications, or mods, to the engine, drive train, intake and exhaust components add up to provide phenomenal performance gains that can be measured as horsepower and torque increases, which yield a competitive advantage, and result in reduced run times. In biology, proteins undergo modifications that alter their function. Some proteins require the modifications in order to perform their function effectively, whether it’s a pro-protein that is cleaved to produce an active enzyme, or a protein that is phosphorylated to facilitate a signaling process. Other proteins, such as histones, undergo modifications that regulate gene expression and alter cellular function. There are several post translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination that impact protein function and activity. As a result, the analysis of proteins and their post-translational modifications are particularly important for the study of normal and disease-associated processes. New antibodies to detect phospho Histidines are now available from EMD Millipore."
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持