产品名称
抗-多巴胺D2受体（DRD2）抗体，克隆2B9, clone 3D9, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
3D9, monoclonal
species reactivity
rat
species reactivity (predicted by homology)
human (immunogen homology)
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype
IgMκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DRD2(1813)
rat ... Drd2(24318)
Analysis Note
对照
大鼠脊髓组织裂解物
大鼠脊髓组织裂解物
通过蛋白质印迹法在大鼠脊髓组织裂解物中进行评估。
蛋白质印迹分析：5 µg/mL的该抗体在10 µg大鼠脊髓组织裂解物上检测到多巴胺D2受体。
蛋白质印迹分析：5 µg/mL的该抗体在10 µg大鼠脊髓组织裂解物上检测到多巴胺D2受体。
Application
免疫细胞化学分析：独立实验室使用了一个先前批次来检测Ntera-2细胞和大鼠脑神经元中的多巴胺D2受体。 由Wolfson Centre for Inherited Neuromuscular Disease的Glenn Morris提供。
经验证，该抗多巴胺D2受体（DRD2）抗体（克隆2B9）可用于检测多巴胺D2受体（DRD2）的WB、IC。
General description
中枢神经系统多巴胺能系统的问题被认为是某些神经精神疾病的根本原因。多巴胺D2受体是多巴胺的五种类型（D1至D5）受体之一。该受体的活性由抑制腺苷酸环化酶的G蛋白介导。使用Nurr1和ERK的多巴胺D2受体信号传导可能在中脑多巴胺能神经元发育中起重要作用。有缺陷的D2受体在ROS依赖性高血压病例中很常见。此外，DRD2的缺陷与酒精反应性肌张力障碍，对家族性酒精中毒的易感性不同以及酗酒者自杀风险的促成因素有关。
观测分子量〜50 kDa
Immunogen
对应于人多巴胺D2受体的线性肽。
Other Notes
Physical form
形式：纯化
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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