MABS132
抗GLUT1（CT）抗体，克隆5B12.3
clone 5B12.3, from mouse
别名:
Solute carrier family 2 facilitated glucose transporter member 1, Glucose transporter type 1,erythrocyte/brain, GLUT-1, HepG2 glucose transporter
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
5B12.3, monoclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
human, rat
Citations:
15
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗GLUT1（CT）抗体，克隆5B12.3, clone 5B12.3, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5B12.3, monoclonal
species reactivity
human, rat
packaging
antibody small pack of 25 μL
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
ambient
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC2A1(6513)
Biochem/physiol Actions
该抗体在 C 端识别 GLUT1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
Analysis Note
对照
NGF 处理的 PC-12 细胞裂解液
NGF 处理的 PC-12 细胞裂解液
通过蛋白质印迹在 NGF 处理的 PC-12 细胞裂解液中进行了评估。
蛋白质印迹分析：0.1 µg/mL 的该抗体在 10 µg NGF 处理的 PC-12 细胞裂解液中检测到 GLUT1。
蛋白质印迹分析：0.1 µg/mL 的该抗体在 10 µg NGF 处理的 PC-12 细胞裂解液中检测到 GLUT1。
Application
免疫组化分析： 一个代表批次以 1：1,000 的稀释度在大鼠小脑和人小脑组织中检测到 GLUT1。
抗 GLUT1（C末端）抗体，克隆 5B12.3 是抗 GLUT1（C 末端）的抗体，用于蛋白质印迹 & IHC。
研究子类别
发育信号转导
发育信号转导
研究类别
信号传导
信号传导
General description
GLUT（葡萄糖转运蛋白）是一个完整的膜蛋白家族，可促进细胞摄取葡萄糖。它们是参与将葡萄糖转运到大多数细胞中的整合膜糖蛋白。七种类型的葡萄糖转运载体蛋白，称为GLUT 1至7，有助于葡萄糖跨细胞膜转运。葡萄糖转运蛋白的分子克隆已鉴定出一系列紧密相关的基因，这些基因编码至少7种蛋白，这些蛋白表现出高度的氨基酸同源性（45％至65％），分子量均在40至60 kDa 之间。GLUT1 在成人组织中的组成型或基础葡萄糖摄取中起作用，并且是胚胎和胎儿组织中的主要葡萄糖转运蛋白。它有两种形式：55 kDa 和 45 kDa。55 kDa 形式的 GLUT1 调节葡萄糖从血液穿过血脑屏障（BBB）内皮细胞进入大脑，而 45 kDa 形式的 GLUT1 主要调节非血管神经胶质葡萄糖的摄取。
可观察到约54 kDa的条带
Immunogen
对应于人 GLUT1 的 C 端的 KLH 偶联的线性肽。
表位：C端
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
纯化的小鼠单克隆IgG1κ，溶于含0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl和0.05％叠氮化钠的缓冲液中。
蛋白G纯化
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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