ligand
(Sulfonic acid (strong cationic), t-butyl (weak HIC/hydrophobic))
质量水平
物料
housing (Copolymer of styrene and phenylene ether)
resin (Polyacrylamide hydrogel (microporous polymer) reinforced with polybutylene terephthalate substrate)
无菌性
non-sterile
产品线
Natrix®
参数
≤10 MV/min max. flow rate
5 bar pressure
75 psi max. pressure
membrane volume
124 mL , nominal
基质
Polyacrylamide hydrogel (microporous polymer) reinforced with polybutylene terephthalate substrate base material
孔径
0.4 μm pore size
容量
>200 mg binding capacity (BSA/ml of membrane)(Up to 1000g/L load capacity in frontal mode)
应用
mAb
pharmaceutical
viral therapy
一般描述
The Natrix® CH Pilot is a membrane chromatography device that can be used for clinical and/or small scale manufacturing activities.
It contains Natrix® CH membrane, a high-capacity cation exchange chromatography membrane.
It contains Natrix® CH membrane, a high-capacity cation exchange chromatography membrane.
应用
Frontal displacement
Bind-and-elute
Bind-and-elute
特点和优势
- Unique Selectivity: excellent aggregate removal in flow-through mode.
- High Binding at Fast Flow-Rates: Natrix® CH membrane has 5x the binding capacity versus the competition at similar residence times.
- Ready to Process: saves time by eliminating the need for column packing required of traditional resins, simply prime the device and begin purifying.
法律信息
NATRIX is a registered trademark of Merck KGaA, Darmstadt, Germany
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