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Merck
CN

PCC100C05

Pellicon® Capsule with Ultracel® Membrane

pore size 100 kDa, C Screen, 0.5 m²

别名:

Pellicon® Capsule with Ultracel® Membrane

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UNSPSC Code:
41104903

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产品名称

Pellicon®胶囊，带Ultracel®膜, Feed: 3/4" Sanitary Flange Retentate: 3/4" Sanitary Flange Permeate: 3/4" Sanitary Flange

material

EPDM rubber seal, PPO/PS blend (core), PPO/PS blend housing, TPE seal, composite regenerated cellulose (CRC) membrane, epoxy adhesive, polyester screen, polypropylene screen, polyurethane adhesive

sterility

sterile; γ-irradiated

product line

Pellicon®

storage condition

room temperature (15-30°C)

parameter

4-6 L/min-m2 flow rate, 45 psi max. transmembrane pressure (3.1 bar) at 4-30 °C (Forward), 80 psi max. inlet pressure (5.5 bar) at 4 - 30 °C

technique(s)

ultrafiltration: suitable

L

35.3 cm (13.9 in.)

diam.

5.7 cm (2.3 in.)

filtration area

0.5 m2

screen size

, Type C screen (coarse screen)

volume

118 mL , in feed channel, 133 mL , in permeate channel

impurities

≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m2)

matrix

Ultracel®

pore size

100 kDa

pH range

2-13

Quality Level

400

fitting

inlet/outlet connection (Feed: 3/4" Sanitary Flange), inlet/outlet connection (Permeate: 3/4" Sanitary Flange), inlet/outlet connection (Retentate: 3/4" Sanitary Flange)

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General description

The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.

Application

Viral Gene Therapies, Vaccines, Concentration, Diafiltration, Buffer exchange, Protein purification, mRNA

Features and Benefits

Plug ′n play, holderless design - easy to install, safe to remove
Gamma sterilized and preservative-free - ready to process in minutes
True single-use, self-contained capsule - fast, safe, and flexible batch turnaround
Proven Ultracel® membrane and C screen - high recovery, superior mass transfer, solvent resistance
Pellicon® TFF proven performance - true linear scalability within Pellicon® TFF families

Packaging

A foam clamshell is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is placed on a tray and then individually boxed.

Other Notes

The Emprove® Program complements the product portfolio through

Comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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商品

Scalable Tangential Flow Filtration (TFF) for Downstream Processing of Viral Vectors for Gene Therapy and Vaccine Production

Our overview of scalable tangential flow filtration for viral vector production will provide key considerations for developing and optimizing your downstream process.

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