01042
N-乙酰基-L-半胱氨酸甲酯
≥90% (HPLC)
别名:
N-acetyl-L-cysteine methyl ester
质量水平
方案
≥90% (HPLC)
表单
powder or crystals
旋光性
[α]20/D −24.0±3°, c = 1% in methanol
反应适用性
reaction type: solution phase peptide synthesis
颜色
white to faint yellow
mp
77-81 °C
应用
peptide synthesis
SMILES字符串
COC(=O)[C@H](CS)NC(C)=O
InChI
1S/C6H11NO3S/c1-4(8)7-5(3-11)6(9)10-2/h5,11H,3H2,1-2H3,(H,7,8)/t5-/m0/s1
InChI key
QTKAQJWFVXPIFV-YFKPBYRVSA-N
相关类别
其他说明
硫转移剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Renu A Kowluru et al.
Laboratory investigation; a journal of technical methods and pathology, 96(10), 1040-1049 (2016-07-28)
Diabetes elevates matrix metalloproteinase-9 (MMP-9) in the retina and its capillary cells, and activated MMP-9 damages mitochondria, accelerating retinal capillary cell apoptosis, a phenomenon which precedes the development of retinopathy. Diabetes also favors epigenetic modifications regulating the expression of many
A. Gilman et al.
Tetrahedron Letters, 33, 1751-1751 (1993)
Jianfen Guo et al.
The Journal of biological chemistry, 286(8), 6500-6509 (2010-12-16)
Protein kinase D (PKD) exists as a family of structurally related enzymes that are activated through similar phosphorylation-dependent mechanisms involving protein kinase C (PKC). While individual PKD isoforms could in theory mediate distinct biological functions, previous studies identify a high
Shinji Hatakeyama et al.
Skeletal muscle, 6, 26-26 (2016-07-28)
Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as
Amy E M Beedle et al.
Nature communications, 9(1), 3155-3155 (2018-08-10)
Mechanical force modifies the free-energy surface of chemical reactions, often enabling thermodynamically unfavoured reaction pathways. Most of our molecular understanding of force-induced reactivity is restricted to the irreversible homolytic scission of covalent bonds and ring-opening in polymer mechanophores. Whether mechanical
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