07270
6-氨基己酸甲酯 盐酸盐
≥99.0% (AT)
别名:
Methyl 6-aminocaproate 盐酸盐
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关于此项目
线性分子式:
NH2(CH2)5COOCH3 · HCl
化学文摘社编号:
分子量:
181.66
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3687692
产品名称
6-氨基己酸甲酯 盐酸盐, ≥99.0% (AT)
InChI
1S/C7H15NO2.ClH/c1-10-7(9)5-3-2-4-6-8;/h2-6,8H2,1H3;1H
SMILES string
Cl.COC(=O)CCCCCN
InChI key
YSLDOTFAFZJPOC-UHFFFAOYSA-N
assay
≥99.0% (AT)
form
powder or crystals
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
117-124 °C
application(s)
peptide synthesis
Quality Level
Application
Methyl 6-aminohexanoate hydrochloride is used to synthesize papain-catalyzed peptides.
General description
Methyl 6-aminohexanoate hydrochloride also known as Methyl 6-aminocaproate hydrochloride, is commonly used in the solution-phase peptide synthesis.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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K Yazawa
Polymers, 8, 194-194 (2016)
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Molecular pharmaceutics, 15(9), 3654-3663 (2018-03-16)
Herein, the biodegradable micelle-forming amphiphilic N-(2-hydroxypropyl) methacrylamide (HPMA)-based polymer conjugates with the anticancer drug doxorubicin (Dox) designed for enhanced tumor accumulation were investigated, and the influence of their stability in the bloodstream on biodistribution, namely, tumor uptake, and in vivo
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Martin Studenovský et al.
Anticancer research, 35(2), 753-757 (2015-02-11)
In the present study, we describe the synthesis and physicochemical properties of a novel pH- and thermoresponsive micellar drug delivery system for an anticancer ellipticinium derivative based on the triblock copolymer poly(ethylene oxide)-block-[tert-butylacrylamide-co-6-(N-methacryloylamino)hexanoic acid hydrazide]-block-poly(ethylene oxide). The system was designed
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