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Merck
CN

07270

6-氨基己酸甲酯 盐酸盐

≥99.0% (AT)

别名:

Methyl 6-aminocaproate 盐酸盐

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关于此项目

线性分子式:
NH2(CH2)5COOCH3 · HCl
化学文摘社编号:
分子量:
181.66
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3687692
Assay:
≥99.0% (AT)
Form:
powder or crystals
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Quality Level

assay

≥99.0% (AT)

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

117-124 °C

application(s)

peptide synthesis

SMILES string

Cl.COC(=O)CCCCCN

InChI

1S/C7H15NO2.ClH/c1-10-7(9)5-3-2-4-6-8;/h2-6,8H2,1H3;1H

InChI key

YSLDOTFAFZJPOC-UHFFFAOYSA-N

General description

Methyl 6-aminohexanoate hydrochloride also known as Methyl 6-aminocaproate hydrochloride, is commonly used in the solution-phase peptide synthesis.

Application

Methyl 6-aminohexanoate hydrochloride is used to synthesize papain-catalyzed peptides.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Papain-catalyzed synthesis of polyglutamate containing a nylon monomer unit
K Yazawa
Polymers, 8, 194-194 (2016)
Petr Chytil et al.
Molecular pharmaceutics, 15(9), 3654-3663 (2018-03-16)
Herein, the biodegradable micelle-forming amphiphilic N-(2-hydroxypropyl) methacrylamide (HPMA)-based polymer conjugates with the anticancer drug doxorubicin (Dox) designed for enhanced tumor accumulation were investigated, and the influence of their stability in the bloodstream on biodistribution, namely, tumor uptake, and in vivo
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via



全球贸易项目编号

货号GTIN
07270-25G04061832593180
07270-100G04061832593173