08339
5-氨基乙酰丙酸盐 盐酸盐
≥97.0% (AT)
别名:
δ-氨基乙酰丙酸盐 盐酸盐, 5-氨基-4-氧代戊酸 盐酸盐, 5-氨基乙酰丙酸盐 盐酸盐, ALA
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关于此项目
线性分子式:
NH2CH2C(O)CH2CH2COOH · HCl
化学文摘社编号:
分子量:
167.59
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
226-679-5
Beilstein/REAXYS Number:
3690651
MDL number:
产品名称
5-氨基乙酰丙酸盐 盐酸盐, ≥97.0% (AT)
InChI key
ZLHFONARZHCSET-UHFFFAOYSA-N
InChI
1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
SMILES string
Cl[H].NCC(=O)CCC(O)=O
assay
≥97.0% (AT)
form
powder or crystals
impurities
≤2% water
color
white to faint yellow
mp
~150 °C (dec.)
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
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Application
5-氨基乙酰丙酸盐酸盐被用作培养大肠杆菌细胞的补充剂，用于血红素的生物合成。
Biochem/physiol Actions
5-氨基乙酰丙酸(5-ALA)可能与谷氨酸、γ-氯基丁酸(GABA)、二肽、三肽等多种转运体以及血脑屏障中的有机转运体相互作用。它还可作为叶绿素和血红素中卟啉合成的前体。5-ALA表现出植物生长调控活性。
血红素生物合成中间体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
农药列管产品
此项目有
5-Aminolevulinic acid and the blood-brain barrier-A review
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Medical Laser Application, 18(1), 36-40 (2003)
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The British journal of dermatology, 171(5), 1172-1180 (2014-08-12)
Daylight-mediated photodynamic therapy (DL-PDT) using methyl-5-aminolaevulinate (MAL) is effective for thin, grade I, actinic keratoses (AK). There are no published studies of other photosensitizers used in DL-PDT. To compare the efficacy and adverse effects of 5-aminolaevulinic acid nanoemulsion (BF-200 ALA)
Hidetoshi Takahashi et al.
The Journal of dermatology, 41(8), 729-731 (2014-08-08)
Photodynamic therapy (PDT) is useful for superficial skin tumors such as actinic keratosis and Bowen disease. Although PDT is non-surgical and easily-performed treatment modality, irradiation apparatus is large and expensive. Using 7, 12-dimethylbenz[a]anthracene (DMBA) and 12-ο-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin papilloma
Zhimin Yang et al.
PloS one, 9(12), e116283-e116283 (2015-01-01)
The objectives of this study were to determine whether foliar application of a chlorophyll precursor, 5-aminolevulinic acid (ALA), could mitigate salinity stress damages in perennial grass species by regulating photosynthetic activities, ion content, antioxidant metabolism, or metabolite accumulation. A salinity-sensitive
Giovanni Pagano et al.
International journal of molecular sciences, 15(11), 20169-20208 (2014-11-08)
An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed "mitochondrial nutrients" (MN), such as α-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and l-carnitine (CARN) (or its derivatives) have been tested in
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