1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐

Name: 1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐
Brand: SIAL

≥97.0% (TLC), for peptide synthesis

别名:

PyBOP^®

登录查看公司和协议定价

About This Item

线性分子式:

C₁₈H₂₈N₆OP · PF₆

CAS Number:

128625-52-5

分子量:

520.39

Beilstein:

3584612

MDL编号:

MFCD00077411

UNSPSC代码:

12352101

PubChem化学物质编号:

329749882

NACRES:

NA.22

主要文件

查看所有文档

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

Product Name

1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐, purum, ≥97.0% (TLC)

等级

purum

质量水平

200

方案

≥97.0% (TLC)

表单

solid

反应适用性

reaction type: Coupling Reactions

mp

~150 °C
154-156 °C (dec.) (lit.)

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5

InChI

1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1

InChI key

VIAFLMPQBHAMLI-UHFFFAOYSA-N

正在寻找类似产品? 访问产品对比指南

一般描述

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.

应用

BOP 偶联剂类似物，不产生致癌副产物 HMPA。

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:

As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.
Synthesis of structured pure triacylglycerol (TAG) regioisomers.
As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.
Synthesis of herceptin- nanoparticles.