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Merck
CN

12806

O -(苯并三唑-1-基)- N,N,N′,N′-四甲基脲四氟硼酸盐

≥97.0% (N), solid, for peptide synthesis

别名:

TBTU, 苯并三唑四甲基四氟硼酸

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关于此项目

线性分子式:
C11H16N5O · BF4
化学文摘社编号:
分子量:
321.08
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
7066325
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产品名称

O -(苯并三唑-1-基)- N,N,N′,N′-四甲基脲四氟硼酸盐, ≥97.0% (N)

InChI

1S/C11H16N5O.BF4/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1

SMILES string

F[B-](F)(F)F.CN(C)\C(On1nnc2ccccc12)=[N+](/C)C

InChI key

JKEKMBGUVUKMQB-UHFFFAOYSA-N

assay

≥97.0% (N)

form

solid

mp

205 °C (dec.) (lit.)

solubility

acetonitrile: 0.1 g/mL, clear, colorless

application(s)

peptide synthesis

storage temp.

2-8°C

Quality Level

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Application

非常适用于固相肽合成的偶联剂。

Other Notes

最近的研究显示,该偶联剂的晶体结构和溶液结构都是 N-氧化胍,而不是铀化合物 ;偶联试剂,最适用于固相多肽合成。

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Flam. Sol. 1 - Skin Sens. 1A

存储类别

4.1A - Other explosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rajni Bala et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 196, 268-273 (2018-02-20)
In the present study, we report a highly sensitive, rapid and low cost colorimetric monitoring of malathion (an organophosphate insecticide) employing a basic hexapeptide, malathion specific aptamer (oligonucleotide) and silver nanoparticles (AgNPs) as a nanoprobe. AgNPs are made to interact
Parvin Zakeri-Milani et al.
EXCLI journal, 16, 650-662 (2017-07-12)
Gemcitabine (Gem) is used as a single agent or in combination with other anticancer agents to treat many types of solid tumors. However, it has many limitations such as a short plasma half-life, dose-limiting toxicities and drug resistance. Cell-penetrating peptides
O-(BENZOTRIAZOL-1-YL)-N, N, N', N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE (TBTU): A NEW REAGENT FOR THE CLEAVAGE OF TETRAHYDROPYRANYL, SILYL AND 4, 4'-D IMETHOXYTRITYL ETHERS.
Ramasamy KS and Averett D.
Synlett, 6, 709-712 (1999)
S. Zimmer et al. et al.
Proc. 22nd Eur. Pept. Symp.: Peptides 1992 null
Antonio Magrì et al.
International journal of molecular sciences, 19(8) (2018-08-15)
The nerve growth factor (NGF) is a neurotrophin essential for the development and maintenance of neurons, whose activity is influenced by copper ions. The NGF protein exerts its action by binding to its specific receptor, TrkA. In this study, a

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