201316
喹哪啶红
Dye content 95 %
别名:
2-[4-(二甲基氨基)苯乙烯]-1-乙基喹啉碘化物
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关于此项目
经验公式(希尔记法):
C21H23IN2
化学文摘社编号:
分子量:
430.33
Beilstein:
3798055
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
表单
powder or crystals
质量水平
组成
Dye content, 95%
技术
titration: suitable
溶解性
ethanol: 1 mg/mL, clear, dark red
λmax
528 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13
InChI
1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1
InChI key
JOLANDVPGMEGLK-UHFFFAOYSA-M
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应用
喹哪啶红已被用作α1-酸糖蛋白(AAG)的荧光探针。
生化/生理作用
喹哪啶红(2-(对-二甲基氨基苯乙烯基)喹啉乙硫醇)是一种非常暗红色或红黑色的粉末。它主要用于调节细胞增殖、与淀粉样蛋白积累有关的疾病的诊断试剂、检测酶活性和牙科漂白材料。此外,喹哪啶红还涉及异常性疼痛和病毒感染性疾病的治疗。在pH 1.4时其呈无色,在pH 3.2时呈红色。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
World Health Organization
The International Pharmacopoeia, 1 (2006)
H Imamura et al.
Pharmaceutical research, 11(4), 566-570 (1994-04-01)
We examined different fluorescent probes suitable for fluorometric determination of alpha 1-acid glycoprotein (AGP) in serum. Quinaldine red (QR) was shown to bind strongly and selectively to AGP. Taking advantage of the enhanced fluorescence of QR in the presence of
Cationic Drug Pharmacokinetics in Diseased Livers Determined by Fibrosis Index, Hepatic Protein Content, Microsomal Activity, and Nature of Drug
Hung D Y
Journal of Pharmacology and Experimental Therapeutics, 301, 1079-1087 (2002)
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