201316
喹哪啶红
Dye content 95 %
别名:
2-[4-(二甲基氨基)苯乙烯]-1-乙基喹啉碘化物
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关于此项目
经验公式（希尔记法）:
C21H23IN2
化学文摘社编号:
分子量:
430.33
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
204-221-5
Beilstein/REAXYS Number:
3798055
MDL number:
产品名称
喹哪啶红, Dye content 95 %
InChI key
JOLANDVPGMEGLK-UHFFFAOYSA-M
InChI
1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1
SMILES string
[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13
form
powder or crystals
composition
Dye content, 95%
technique(s)
titration: suitable
solubility
ethanol: 1 mg/mL, clear, dark red
λmax
528 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
喹哪啶红已被用作α1-酸糖蛋白（AAG）的荧光探针。
Biochem/physiol Actions
喹哪啶红（2-（对-二甲基氨基苯乙烯基）喹啉乙硫醇）是一种非常暗红色或红黑色的粉末。它主要用于调节细胞增殖、与淀粉样蛋白积累有关的疾病的诊断试剂、检测酶活性和牙科漂白材料。此外，喹哪啶红还涉及异常性疼痛和病毒感染性疾病的治疗。在pH 1.4时其呈无色，在pH 3.2时呈红色。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Selective plasma protein binding of antimalarial drugs to a1-acid glycoprotein
Zsila F
Bioorganic & Medicinal Chemistry, 3759-3772 (2008)
Cationic Drug Pharmacokinetics in Diseased Livers Determined by Fibrosis Index, Hepatic Protein Content, Microsomal Activity, and Nature of Drug
Hung D Y
Journal of Pharmacology and Experimental Therapeutics, 301, 1079-1087 (2002)
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been
H Imamura et al.
Pharmaceutical research, 11(4), 566-570 (1994-04-01)
We examined different fluorescent probes suitable for fluorometric determination of alpha 1-acid glycoprotein (AGP) in serum. Quinaldine red (QR) was shown to bind strongly and selectively to AGP. Taking advantage of the enhanced fluorescence of QR in the presence of
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