230987
维多利亚纯蓝 BO
Dye content 90 %
别名:
碱性蓝 7
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关于此项目
经验公式（希尔记法）:
C33H40ClN3
化学文摘社编号:
分子量:
514.14
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
219-232-0
Colour Index Number:
42595
MDL number:
InChI key
ROVRRJSRRSGUOL-UHFFFAOYSA-N
InChI
1S/C33H39N3.ClH/c1-6-34-32-24-23-31(29-13-11-12-14-30(29)32)33(25-15-19-27(20-16-25)35(7-2)8-3)26-17-21-28(22-18-26)36(9-4)10-5;/h11-24H,6-10H2,1-5H3;1H
SMILES string
[Cl-].CCNc1ccc(\C(c2ccc(cc2)N(CC)CC)=C3/C=C\C(C=C3)=[N+](\CC)CC)c4ccccc14
form
powder, crystals or chunks
composition
Dye content, 90%
solubility
95% ethanol: 0.1%, blue to very deep blue
λmax
619 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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General description
维多利亚蓝染料是三氨基二苯基萘甲烷，具有亲脂性阳离子和大型共轭体系。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A Viola et al.
International journal of cancer, 85(5), 733-739 (2000-03-04)
Victoria Blue BO (VB BO) is a new and promising photosensitizer currently being evaluated for photodynamic therapy (PDT). Its photochemical processes are mediated by oxygen radicals, but do not involve singlet oxygen. We used (31)P NMR spectroscopy of VB-BO sensitized
Zong Jie Cui et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 1(12), 1001-1005 (2003-03-29)
The adrenergic agonist phenylephrine (PE) induced typical [Ca2+]i oscillations in freshly isolated rat hepatocytes, and the photodynamic effect of Victoria Blue BO on induced calcium oscillations was investigated. PE induced calcium oscillations disappeared after Victoria Blue BO photodynamic action (in
S M Burrow et al.
Membrane & cell biology, 14(3), 357-366 (2001-05-23)
Victoria Blue BO (VBBO) is thought to exert its photocytotoxic effects via free radical generation. Glutathione and related enzymes are associated with the protection of normal tissues against free-radical damage and have also been implicated in multiple drug resistance. It
J Morgan et al.
Photochemistry and photobiology, 67(1), 155-164 (1998-04-04)
The cationic photosensitizing triaryl methane dye Victoria Blue BO (VBBO) localizes in mitochondria and causes oxidative damage to this organelle during photodynamic therapy (PDT). Oxidative stresses from other photosensitizers induce a variety of stress proteins. The endoplasmic reticulum (ER)-based, calcium-binding
J Morgan et al.
Photochemistry and photobiology, 71(6), 747-757 (2000-06-17)
The relative contribution, to cell death, of photodynamic damage to respiratory proteins (known targets of photodynamic therapy with many photosensitizers) and other cellular sites was examined. The models were a human ovarian carcinoma cell line 2008, and its mitochondrial DNA-deficient
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