230987
维多利亚纯蓝 BO
Dye content 90 %
别名:
碱性蓝 7
表单
powder, crystals or chunks
质量水平
组成
Dye content, 90%
溶解性
95% ethanol: 0.1%, blue to very deep blue
λmax
619 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Cl-].CCNc1ccc(\C(c2ccc(cc2)N(CC)CC)=C3/C=C\C(C=C3)=[N+](\CC)CC)c4ccccc14
InChI
1S/C33H39N3.ClH/c1-6-34-32-24-23-31(29-13-11-12-14-30(29)32)33(25-15-19-27(20-16-25)35(7-2)8-3)26-17-21-28(22-18-26)36(9-4)10-5;/h11-24H,6-10H2,1-5H3;1H
InChI key
ROVRRJSRRSGUOL-UHFFFAOYSA-N
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一般描述
维多利亚蓝染料是三氨基二苯基萘甲烷，具有亲脂性阳离子和大型共轭体系。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
M Wainwright et al.
Journal of chemotherapy (Florence, Italy), 11(1), 61-68 (1999-03-17)
The toxicities and phototoxicities of methylene blue (MB), toluidine blue O (TBO) and Victoria blue BO (VBBO) in a murine mammary tumour cell line (EMT6-S) and a multidrug resistant (MDR) sub-line (EMT6-R) were measured and their efficacy against the resistant
J Morgan et al.
Photochemistry and photobiology, 71(6), 747-757 (2000-06-17)
The relative contribution, to cell death, of photodynamic damage to respiratory proteins (known targets of photodynamic therapy with many photosensitizers) and other cellular sites was examined. The models were a human ovarian carcinoma cell line 2008, and its mitochondrial DNA-deficient
S M Burrow et al.
Membrane & cell biology, 14(3), 357-366 (2001-05-23)
Victoria Blue BO (VBBO) is thought to exert its photocytotoxic effects via free radical generation. Glutathione and related enzymes are associated with the protection of normal tissues against free-radical damage and have also been implicated in multiple drug resistance. It
J Morgan et al.
Photochemistry and photobiology, 67(1), 155-164 (1998-04-04)
The cationic photosensitizing triaryl methane dye Victoria Blue BO (VBBO) localizes in mitochondria and causes oxidative damage to this organelle during photodynamic therapy (PDT). Oxidative stresses from other photosensitizers induce a variety of stress proteins. The endoplasmic reticulum (ER)-based, calcium-binding
A Viola et al.
International journal of cancer, 85(5), 733-739 (2000-03-04)
Victoria Blue BO (VB BO) is a new and promising photosensitizer currently being evaluated for photodynamic therapy (PDT). Its photochemical processes are mediated by oxygen radicals, but do not involve singlet oxygen. We used (31)P NMR spectroscopy of VB-BO sensitized
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