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Merck
CN

282820

原卟啉九锌（二）

guanylate cyclase inhibitor

别名:

3,7,12,17-四甲基-8,13-二乙烯基-2,18-卟吩二丙酸, 8,13-二乙烯基-3,7,12,17-四甲基-21,23-卟吩-2,18-二丙酸 锌衍生物, 原卟啉 IX 锌(II) 络合物

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关于此项目

经验公式（希尔记法）:
C34H32N4O4Zn
化学文摘社编号:
15442-64-5
分子量:
626.03
NACRES:
NA.47
PubChem Substance ID:
24857074
UNSPSC Code:
12171500
EC Number:
239-455-7
MDL number:
MFCD00011612

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产品名称

原卟啉九锌（二）, guanylate cyclase inhibitor

InChI key

FUTVBRXUIKZACV-RGGAHWMASA-L

InChI

1S/C34H34N4O4.Zn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;

SMILES string

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Zn]n34)c(C=C)c5C

assay

≥92% (HPLC)

form

powder

technique(s)

titration: suitable

color

red to very dark red

λmax

426 nm

ε (extinction coefficient)

≥10000 at 585-591 nm in pyridine
≥12000 at 548-554 nm in pyridine
≥135000 at 423-429 nm in pyridine

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

相关类别

Application

抑制可溶性鸟苷酸环化酶。
研究了ZnPP处理的正常人黑素细胞中的细胞黑色素含量。1它被用作一项研究的标准，在该研究中，铁缺乏红细胞生成中ZnPP的过量形成由血液荧光计测定。

General description

原卟啉ⅸ锌（ⅱ）（ZnPP）是一种抗氧化酶血红素加氧酶-1。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCQ4038
MKCL3047
MKCH9486
MKBV8659V
MKBR4657V

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