32830
L-2,4-二氨基丁酸 二盐酸盐
≥95.0%
别名:
(2S)-2,4-Diaminobutanoic acid dihydrochloride, L-2,4-Diaminobutanoic acid dihydrochloride
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关于此项目
线性分子式:
NH2CH2CH2CH(NH2)COOH · 2HCl
化学文摘社编号:
分子量:
191.06
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-542-0
Beilstein/REAXYS Number:
5763078
MDL number:
产品名称
L-2,4-二氨基丁酸 二盐酸盐, ≥95.0%
InChI key
CKAAWCHIBBNLOJ-QTNFYWBSSA-N
InChI
1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H/t3-;;/m0../s1
SMILES string
Cl.Cl.NCC[C@H](N)C(O)=O
assay
≥95.0% (AT)
≥95.0%
optical activity
[α]20/D +14.5±1.5°, c = 3.67% in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
197-200 °C (dec.)
solubility
water: soluble 0.5 g/10 mL
application(s)
peptide synthesis
Quality Level
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Application
L-2,4-二氨基丁酸二盐酸盐可用于通过 HPLC-FD、UHPLC-UV、UHPLC-MS 和三重四极杆串联质谱法（UHPLC-MS/MS）从二氨基酸中区分出 β-N-甲基氨基-L-丙氨酸。它适用于定量海鲜中神经毒素 β-N-甲基氨基-L-丙氨酸（BMAA）。它可用作氨基酸分析的内标
Disclaimer
可能会释放出 HCl
General description
L-2,4-二氨基丁酸二盐酸盐是非天然氨基酸衍生物。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Liying Jiang et al.
Scientific reports, 4, 6931-6931 (2014-11-07)
The neurotoxin β-N-methylamino-L-alanine (BMAA) produced naturally by cyanobacteria, diatoms and dinoflagellates can be transferred and accumulated up the food chain, and may be a risk factor for neurodegenerative diseases. This study provides the first systematic screening of BMAA exposure of
Sun-Jung Kim et al.
International journal of systematic and evolutionary microbiology, 61(Pt 1), 155-159 (2010-02-23)
A Gram-positive, non-motile bacterium, designated KSL51201-037(T), was isolated from Anyang stream, Republic of Korea, and was characterized using a polyphasic taxonomic approach. Comparative 16S rRNA gene sequence analysis showed that strain KSL51201-037(T) belonged to the family Microbacteriaceae of the class
Qing Li et al.
Organic letters, 12(5), 1080-1083 (2010-02-11)
The first highly diastereo- and enantioselective catalytic asymmetric Michael addition of glycine derivatives to nitroalkenes have been developed. The enantioselectivity of ortho-substituted products can be significantly improved by using a new 1,2-P,N-ferrocene ligand L5. The alpha,gamma-diaminoacid derivative was obtained without
Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases.
Rajesh Gumpena et al.
ChemMedChem, 6(11), 1971-1976 (2011-10-26)
S A Banack et al.
Toxicon : official journal of the International Society on Toxinology, 57(5), 730-738 (2011-02-19)
β-N-methylamino-L-alanine (BMAA) is produced by diverse taxa of cyanobacteria, and has been detected by many investigators who have searched for it in cyanobacterial blooms, cultures and collections. Although BMAA is distinguishable from proteinogenic amino acids and its isomer 2,4-DAB using
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