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Merck
CN

365548

直接红(零售包装)

Dye content 25 %

别名:

天狼星红

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关于此项目

经验公式(希尔记法):
C45H26N10Na6O21S6
化学文摘社编号:
分子量:
1373.07
EC Number:
220-027-3
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Colour Index Number:
35780
Beilstein/REAXYS Number:
8185575
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产品名称

直接红(零售包装), Dye content 25 %

InChI key

YIQKLZYTHXTDDT-IJPLDVMMSA-H

InChI

1S/C45H32N10O21S6.6Na/c56-43-33-13-5-27(17-23(33)19-39(81(71,72)73)41(43)54-52-35-15-7-29(21-37(35)79(65,66)67)50-48-25-1-9-31(10-2-25)77(59,60)61)46-45(58)47-28-6-14-34-24(18-28)20-40(82(74,75)76)42(44(34)57)55-53-36-16-8-30(22-38(36)80(68,69)70)51-49-26-3-11-32(12-4-26)78(62,63)64;;;;;;/h1-22,56-57H,(H2,46,47,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76);;;;;;/q;6*+1/p-6/b50-48+,51-49+,54-52+,55-53+;;;;;;

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Oc1c(\N=N\c2ccc(cc2S([O-])(=O)=O)\N=N\c3ccc(cc3)S([O-])(=O)=O)c(cc4cc(NC(=O)Nc5ccc6c(O)c(\N=N\c7ccc(cc7S([O-])(=O)=O)\N=N\c8ccc(cc8)S([O-])(=O)=O)c(cc6c5)S([O-])(=O)=O)ccc14)S([O-])(=O)=O

form

powder

composition

Dye content, 25%

technique(s)

titration: suitable

color

dark brown

λmax

528 nm

ε (extinction coefficient)

≥12000 at 277-283 nm in H2O
≥15000 at 223-235 nm in H2O
≥32000 at 524-530 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

直接红 80 已被用作制备饱和苦味酸的成分,用于免疫组织化学检测和定量肝组织中的胶原蛋白。其他应用程序包括-
  • 淀粉样蛋白的检测
  • 使用图像分析方法定量胶原的天狼星红瑞德-范吉森法
  • 在明矾苏木精中取代曙红的复染应用

General description

Direct Red 80(C.I.35780)是一种极亲水、非常大的四偶氮六磺酸阴离子染料,具有大的平面芳香体系。它也被称为天狼星红 F3B、氯胺坚牢红 7BLN 或 5BRL、杜拉唑亮红 B、滂胺坚牢红 7BNL 和天狼星红。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Degradation of a Textile Dye C. I. Direct Red 80 by
Electrochemical Processes
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Lopes A, et al.
Portugaliae Electrochimica Acta , 279-294 (2004)
BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation.
Matsubara T, et al.
The Journal of Biological Chemistry, 283(43), 29119-29125 (2008)
A F Tarantal et al.
The European respiratory journal, 36(4), 907-914 (2010-03-31)
Altered transforming growth factor (TGF)-β expression levels have been linked to a variety of human respiratory diseases, including bronchopulmonary dysplasia and pulmonary fibrosis. However, a causative role for aberrant TGF-β in neonatal lung diseases has not been defined in primates.
Jill J Weyers et al.
PloS one, 15(1), e0227780-e0227780 (2020-01-17)
The engraftment of human stem cell-derived cardiomyocytes (hSC-CMs) is a promising treatment for remuscularizing the heart wall post-infarction, but it is plagued by low survival of transplanted cells. We hypothesize that this low survival rate is due to continued ischemia
Kandice R Levental et al.
Cell, 139(5), 891-906 (2009-11-26)
Tumors are characterized by extracellular matrix (ECM) remodeling and stiffening. The importance of ECM remodeling to cancer is appreciated; the relevance of stiffening is less clear. We found that breast tumorigenesis is accompanied by collagen crosslinking, ECM stiffening, and increased

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