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Merck
CN

410217

2′,7′-二氯荧光素

ACS reagent

别名:

二氯荧光素;荧光素27

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关于此项目

经验公式(希尔记法):
C20H10Cl2O5
化学文摘社编号:
分子量:
401.20
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
200-968-6
Beilstein/REAXYS Number:
58009
MDL number:
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grade

ACS reagent

Quality Level

form

powder

technique(s)

titration: suitable

color

orange to red-brown, powder

mp

280 °C (dec.) (lit.)

solubility

alcohol: passes test

density

0.790 g/cm3

λmax

509 nm

suitability

passes test for adsorption indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1cc2Oc3cc(O)c(Cl)cc3C4(OC(=O)c5ccccc45)c2cc1Cl

InChI

1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H

InChI key

VFNKZQNIXUFLBC-UHFFFAOYSA-N

General description

2′,7′-二氢荧光素是一种氧化敏感荧光探针。

Application

2′,7′-二氯荧光素已用于测量细胞中ROS(活性氧)的形成。 它已被用作荧光底物,以研究唾液样本及颌下腺提取物的过氧化物酶的活性。


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Janaína Kolling et al.
Cardiovascular toxicology, 11(1), 67-73 (2010-11-16)
Hyperhomocysteinemia is a risk factor for cardiovascular disease, stroke, and thrombosis; however, the mechanisms by which homocysteine triggers these dysfunctions are not fully understood. In the present study, we investigated the effect of chronic hyperhomocysteinemia on some parameters of oxidative
Aleksey Rukavishnikov et al.
Analytical biochemistry, 419(1), 9-16 (2011-08-27)
Cephalosporin was used to synthesize soluble and precipitating fluorogenic β-lactam substrates that demonstrated differential catalytic hydrolysis by three different subtypes of β-lactamase: TEM-1 (class A), p99 (class C), and a Bacillus cereus enzyme sold by Genzyme (class B). The most
Olga N Pakhomova et al.
Archives of biochemistry and biophysics, 527(1), 55-64 (2012-08-23)
Nanosecond pulsed electric field (nsPEF) is a novel modality for permeabilization of membranous structures and intracellular delivery of xenobiotics. We hypothesized that oxidative effects of nsPEF could be a separate primary mechanism responsible for bioeffects. ROS production in cultured cells



全球贸易项目编号

货号GTIN
410217-10G04061832011332
410217-1G04061832011356