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Merck
CN

45753

克菌星(氟硅唑)

PESTANAL®, analytical standard

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经验公式(希尔记法):
C16H15F2N3Si
化学文摘社编号:
分子量:
315.39
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5824097
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InChI

1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3

SMILES string

C[Si](Cn1cncn1)(c2ccc(F)cc2)c3ccc(F)cc3

InChI key

FQKUGOMFVDPBIZ-UHFFFAOYSA-N

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

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General description

Flusilazole is an organosilicon fungicide, which belongs to the class of sterol demethylation inhibitors. Its mode of action involves the inhibition of lanosterol 1,4-α-demethylation in fungal sterol biosynthesis.

Application

Flusilazole may be used as a reference standard for the determination of flusilazole in water samples using solid-phase extraction (SPE) method using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

农药列管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of pyrazole and pyrrole pesticides in environmental water samples by solid-phase extraction using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography.
Ma J, et al.
Journal of Chromatographic Science, 53(2), 380-384 (2014)
Sensitivity of Venturia inaequalis isolates from British Columbia to flusilazole and myclobutanil.
Sholberg LP and Haag DP
Canadian Journal of Plant Pathology, 15(2), 102-106 (1993)
J M Trzaskos et al.
Antimicrobial agents and chemotherapy, 33(8), 1228-1231 (1989-08-01)
Flusilazole inhibits the 14 alpha-demethylation of [24,25-3H-2]dihydrolanosterol by yeast and rat liver cell-free preparations. The 50% inhibitory concentration of demethylation shows that the yeast system is 100 times more sensitive than the rat system. Purified rat liver P-45014DM is about
Shuang Yu et al.
Bulletin of environmental contamination and toxicology, 86(3), 319-322 (2011-02-04)
A simple, quick and reliable residue analytical method for flusilazole in apple and soil was developed in this study. The samples were extracted with acetonitrile and determined by liquid chromatography with UV detection. The LOQ of the method was 0.02
J J Anderson et al.
Journal of agricultural and food chemistry, 47(6), 2439-2446 (2000-05-04)
[Phenyl(U)-(14)C] and [triazole(3)-(14)C]flusilazole ([(bis 4-fluorophenyl)]methyl(1H-1,2,4-triazole-1-ylmethyl)silane; I) were extensively metabolized when fed to lactating goats (Capra hircus). The primary metabolites identified in goat tissues and milk were bis(4-fluorophenyl)(methyl)silanol (II) and 1H-1,2,4-triazole (III). Concentrations of total radiolabeled residues in the milk ranged

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