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Merck
CN

46148

Supelco

肾上腺酮

VETRANAL®, analytical standard

别名:

11β,21-二羟丙酮-4-孕烯-3,20-二酮, 11β,21-二羟基黄体酮, 4-孕烯-11β,21-二醇-3,20-二酮, Kendall化合物B, Reichstein物质H

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关于此项目

经验公式(希尔记法):
C21H30O4
化学文摘社编号:
分子量:
346.46
Beilstein:
2339601
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

产品线

VETRANAL®

方案

≥98% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

179-183 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO

InChI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

InChI key

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

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一般描述

Corticosterone is one of the principal steroids secreted by the rat adrenal gland and found in rat plasma.

应用

Corticosterone may be used as a reference standard in the determination of corticosterone in plasma samples using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of plasma corticosterone using high-performance liquid chromatography.
Woodward HJC and Emery WP
Journal of Chromatography. B, Biomedical Sciences and Applications, 419(2), 280-284 (1987)
Selective retention of corticosterone by limbic structures in rat brain.
McEwen SB, et al.
Nature, 220(5170), 911-911 (1968)
The estimation of small amounts of corticosterone in rat plasma.
Zenker N and Bernstein ED
The Journal of Biological Chemistry, 231(2), 695-701 (1958)
Damiano Azzinnari et al.
Neuropharmacology, 85, 328-341 (2014-06-08)
In neuropsychiatry, animal studies demonstrating causal effects of environmental manipulations relevant to human aetiology on behaviours relevant to human psychopathologies are valuable. Such valid models can improve understanding of aetio-pathophysiology and preclinical discovery and development of new treatments. In depression
E N de Haas et al.
Poultry science, 92(9), 2259-2269 (2013-08-21)
Little is known about the relationship between welfare traits and production in laying hen parent stock (PS). In commercial laying hens and pure lines, it is known that aspects associated with reduced welfare such as high fear, stress, and feather

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Milli-Q® ultrapure water systems deliver water free of organic contaminants , including hormones present in a lab's tap water, making it suitable for the most sensitive LC-MS/MS analyses.

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