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Merck
CN

46401

环己酰亚胺，大包装

PESTANAL®, analytical standard

别名:

3- [2-（3,5-二甲基-2-氧代环己基）-2-羟乙基]戊二酰亚胺, 放线菌酮, 纳拉霉素A

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关于此项目

经验公式（希尔记法）:
C15H23NO4
化学文摘社编号:
66-81-9
分子量:
281.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757163
EC Number:
200-636-0
Beilstein/REAXYS Number:
88868
MDL number:
MFCD00082346

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产品名称

环己酰亚胺，大包装, PESTANAL®, analytical standard

InChI key

YPHMISFOHDHNIV-FSZOTQKASA-N

InChI

1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

SMILES string

[H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC2CC(=O)NC(=O)C2

grade

analytical standard

description

mixture of stereo isomers

product line

PESTANAL®

assay

≥95% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: slightly soluble

antibiotic activity spectrum

fungi

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

mode of action

protein synthesis | interferes

storage temp.

−20°C

Quality Level

100

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相关类别

Application

环己酰亚胺可能有以下用途：
  • 评估环己酰亚胺作为 Optisol GS 补充剂的抗真菌疗效和安全性
  • 研究环己酰亚胺对切叶蚁工蚁的影响
  • 研究链霉素、环己酰亚胺、菌唑、克菌丹、呋喃丹、乐果和五氯硝基苯对土壤微生物的影响
  • 半干旱草地一氧化二氮生产的真菌控制研究
  • 链霉素和环己酰亚胺在土壤中的活性及其降解研究

Biochem/physiol Actions

作用机制：真核生物中的翻译抑制导致细胞生长停滞和细胞死亡。CHX被广泛用于抗CHX的酵母和真菌菌株的选择、蛋白质合成的受控抑制以检测短寿命蛋白质和蛋白质表达的超诱导作用、以及诱导凋亡或促进通过死亡受体诱导的凋亡。

活性谱：具有抑制酵母和真菌如念珠菌、曲霉、酵母菌和青霉的活性

General description

环己酰亚胺是一种具有显著抗真菌特性的抗生素。它由产链霉素的灰色链霉菌菌株产生，并通过抑制蛋白质合成发挥作用。它的主要生物学活性是真核生物中的翻译抑制，从而导致细胞生长停滞和细胞死亡。它被用作杀菌剂。
根据废除91/414指令的第1107/2009号法规（EC），环己酰亚胺未被批准在欧盟使用。

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 2 - Muta. 2 - Repr. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN1332
BCCM3154
BCCL9551
BCCL4263
BCCG8626

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