55513
精胺
analytical standard
别名:
N,N′-双(3-氨基丙基)-1,4-丁二胺, 精素, 肌胺, 肝胺
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关于此项目
线性分子式:
NH2(CH2)3NH(CH2)4NH(CH2)3NH2
化学文摘社编号:
分子量:
202.34
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-754-2
Beilstein/REAXYS Number:
1750791
MDL number:
grade
analytical standard
Quality Level
assay
≥99.0% (GC), 97.0-103.0% (T)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤0.5% carbonate, ≤0.5% spermidine
bp
150 °C/5 mmHg (lit.)
mp
28-30 (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
2-8°C
SMILES string
[H]N(CCCN)CCCCN([H])CCCN
InChI
1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2
InChI key
PFNFFQXMRSDOHW-UHFFFAOYSA-N
Application
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
多胺位点混合型 NMDA 受体激动剂/拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 谷氨酸受体激动剂/拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Anthony E Pegg et al.
Cellular and molecular life sciences : CMLS, 67(1), 113-121 (2009-10-28)
Spermine is present in many organisms including animals, plants, some fungi, some archaea, and some bacteria. It is synthesized by spermine synthase, a highly specific aminopropyltransferase. This review describes spermine synthase structure, genetics, and function. Structural and biochemical studies reveal
R Amendola et al.
Current cancer drug targets, 9(2), 118-130 (2009-03-12)
The natural polyamines (PA), putrescine (PUT), spermidine (SPD) and spermine (SPM) are ubiquitous constituents of eukaryotic cells. The increase of PA in malignant and proliferating cells attracted the interest of scientists during last decades, addressing PA depletion as a new
Mg-ATP binding: its modification by spermine, the relevance to cytosolic Mg2+ buffering, changes in the intracellular ionized Mg2+ concentration and the estimation of Mg2+ by 31P-NMR.
D Lüthi et al.
Experimental physiology, 84(2), 231-252 (1999-05-05)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 74124-50MG | 04061833964613 |
| 45678-250MG-R | 04061832341705 |
| 55513-100MG | 04061832582511 |