556416
新亚甲蓝
Dye content ~70 %
别名:
亚甲蓝, 基本蓝24
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关于此项目
经验公式（希尔记法）:
C18H22ClN3S
化学文摘社编号:
分子量:
347.91
颜色索引号:
52030
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
表单
powder, crystals or chunks
组成
Dye content, ~70%
技术
microbe id | staining: suitable
mp
190 °C (dec.) (lit.)
λmax
590 nm
632 nm (2nd)
εmax
≥29000 at 626-634 nm in water
≥30500 at 586-594 nm in water
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C
InChI
1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1
InChI key
NZYCYASKVWSANA-UHFFFAOYSA-M
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应用
新的亚甲蓝N已被用作光敏剂，以对白色念珠菌进行光动力灭活。
生化/生理作用
新亚甲蓝N能与核糖核酸结合、中和和交联。这导致核糖体和残余核糖核酸与线粒体和铁蛋白团共沉淀。这些事件使活性、年轻红细胞在显微镜下可见，呈深蓝色簇合物和细丝，称为网状组织。新亚甲蓝N有助于网织红细胞（含有核糖核酸的红细胞）的计数。
特点和优势
溶剂可溶的阳离子噻嗪染料
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Fernando A Castro et al.
Veterinary surgery : VS, 34(6), 539-542 (2005-12-14)
To evaluate the accuracy of a new technique for perineural injection of the lateral palmar nerve and to determine frequency of inadvertent injection into the carpal synovial sheath with this technique. Prospective experimental study. Thirty equine cadaver forelimbs. Each of
Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice.
Dai T, et al.
Antimicrobial Agents and Chemotherapy, 55, 5710-5710 (2011)
Mari Kono et al.
Clinica chimica acta; international journal of clinical chemistry, 404(2), 105-110 (2009-03-24)
The enumeration of peripheral blood reticulocytes plays an important part in clinical hematology. Although reticulocyte enumeration is currently performed with visible dyes such as New Methylene Blue (NMB), fluorescent dyes, or anti-CD71 (transferrin receptor) antibody, it has not been demonstrated
Hexose monophosphate shunt metabolism in sheep: comparison of fetal, newborn and adult erythrocytes.
N A Noble et al.
Journal of developmental physiology, 3(6), 333-341 (1981-12-01)
Glucose utilization through the hexose monophosphate shunt was measured in erythrocytes from fetal sheep, newborn lambs and adult pregnant sheep. Fetal erythrocytes demonstrate dramatically increased glucose oxidation in the presence of the oxidant new methylene blue. This response declines by
Photodynamic therapy of oral Candida infection in a mouse model.
Freire F, et al.
Journal of Photochemistry and Photobiology. B, Biology, 159, 161-161 (2016)
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