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经验公式(希尔记法):
C4H5NO3
化学文摘社编号:
分子量:
115.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
228-001-3
MDL number:
Beilstein/REAXYS Number:
113913
产品名称
N-羟基丁二酰亚胺, purum, ≥97.0% (T)
InChI key
NQTADLQHYWFPDB-UHFFFAOYSA-N
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
SMILES string
ON1C(=O)CCC1=O
grade
purum
assay
≥97.0% (T)
form
solid
reaction suitability
reaction type: Addition Reactions
mp
95-98 °C (lit.)
95-98 °C
application(s)
peptide synthesis
functional group
imide
Quality Level
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Application
N-羟基丁二酰亚胺(NHS)可以用于以下实验:
- 合成N-琥珀星氩氨-3(2-吡啶二硫代)-酸酯,这是一种异双功能试剂,用于蛋白和蛋白偶联以及脂肪族硫醇插入蛋白。
- 合成长链脂肪酸的NHS酯
- NHS可以活化固定在钛表面的膦酸单层,用于结合蛋白。
Other Notes
可能含有1-3%的丁二酸和或丁二酸酐
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Synthesis of long-chain fatty acyl-CoA thioesters using N-hydroxysuccinimide esters.
Blecher M
Methods in Enzymology, 72, 404-408 (1981)
Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio) propionate, a new heterobifunctional reagent.
Carlsson J
The Biochemical Journal, 173(3), 723-723 (1978)
Kengo Nishi et al.
The Journal of chemical physics, 137(22), 224903-224903 (2012-12-20)
We investigated the relationship between the elastic modulus, G and the reaction probability, p for polymer networks. First, we pointed out that the elastic modulus is expressed by G = {(fp∕2 - 1) + O((p - 1)(2))} Nk(B)T∕V (percolated network
Phosphonic acid monolayers for binding of bioactive molecules to titanium surfaces.
Adden N
Langmuir, 22(19), 8197-8204 (2006)
Burcu Ayoglu et al.
EMBO molecular medicine, 6(7), 918-936 (2014-06-13)
Despite the recent progress in the broad-scaled analysis of proteins in body fluids, there is still a lack in protein profiling approaches for biomarkers of rare diseases. Scarcity of samples is the main obstacle hindering attempts to apply discovery driven
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