59964
组胺
analytical standard
别名:
2-(4-咪唑基)乙胺
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关于此项目
经验公式（希尔记法）:
C5H9N3
化学文摘社编号:
分子量:
111.15
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-100-6
Beilstein/REAXYS Number:
2012
MDL number:
产品名称
组胺, analytical standard
InChI key
NTYJJOPFIAHURM-UHFFFAOYSA-N
InChI
1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
SMILES string
NCCc1c[nH]cn1
grade
analytical standard
assay
≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
impurities
≤4.0% water
color
white to light yellow
bp
167 °C/0.8 mmHg (lit.)
mp
83-84 °C (lit.)
format
neat
storage temp.
−20°C
Quality Level
Gene Information
human ... HRH1(3269)
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Application
有关理想仪器技术的更多信息，参见产品#8242;s分析证书。想要获得更多支持，请联系技术服务部。
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可以使 Ca2+ 移动；H2 的活化可促进神经元中腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。
内源性 H1 和 H2 组胺受体激动剂；可活化一氧化氮合成酶；有效的血管舒张剂。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ye Zhang et al.
Investigative ophthalmology & visual science, 56(1), 563-570 (2015-01-13)
We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
P J Turner et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 25(7), 657-661 (2014-10-10)
Most children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked
Mohamed H Shamji et al.
The Journal of allergy and clinical immunology, 135(4), 913-921 (2014-12-03)
Immunotherapy inhibits basophil histamine release, but the assay is cumbersome, and no one has studied the effects of immunotherapy withdrawal. Intracellular fluorochrome-labeled diamine oxidase (DAO) was used as a novel functional readout of basophil histamine release after immunotherapy. Results were
Ruth Ferstl et al.
Frontiers in bioscience (Landmark edition), 17, 40-53 (2011-12-29)
Histamine influences many cell types involved in the regulation of innate and adaptive immune responses including antigen-presenting cells (APCs), Natural Killer (NK) cells, epithelial cells, T lymphocytes and B lymphocytes. These cells express histamine receptors (HRs) and also secrete histamine
Sten Dreborg
International archives of allergy and immunology, 166(1), 77-80 (2015-03-15)
Skin prick test results are mostly reported as mean wheal diameter obtained with one concentration of allergen. Differences in technique between personnel causes variation in wheal size. The research question was whether the influence of differences in skin prick test
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