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Merck
CN

63175

4-马来酰亚胺基丁酸 N -羟基琥珀酰亚胺酯

≥98.0% (HPLC)

别名:

4-马来酰亚胺基丁酸 N -琥珀酰亚胺酯, N -琥珀酰亚胺基 4-马来酰亚胺基丁酸酯, N-(γ-马来酰亚胺丁酰氧基)琥珀酰亚胺, GMBS

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关于此项目

经验公式(希尔记法):
C12H12N2O6
化学文摘社编号:
分子量:
280.23
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6427689
Assay:
≥98.0% (HPLC)
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Quality Level

assay

≥98.0% (HPLC)

reaction suitability

reagent type: linker

mp

123-129 °C

functional group

NHS ester

storage temp.

2-8°C

SMILES string

O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O

InChI

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

InChI key

PVGATNRYUYNBHO-UHFFFAOYSA-N

Application

一种具有胺和巯基反应性的异双功能交联剂。通常,最初通过在 pH 7.5 (6.5-8.5) 下缓冲的酰胺键与含有伯胺的分子偶联。通过硫醚键在 pH 6.8 (6.5-7.0) 下缓冲的含游离巯基的分子的特异性二次偶联。用于制备酶免疫结合物和半抗原载体分子结合物。提供 7 原子链接器。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiaoying Xue et al.
Biomacromolecules, 14(2), 331-341 (2013-01-11)
PEGylation can improve the protein efficacy by prolonging serum half-life and reducing proteolytic sensitivity and immunogenicity. However, PEGylation may decrease the bioactivity of a protein by interfering with binding of its substrate or receptors. Here, staphylokinase (SAK), a thrombolysis agent



全球贸易项目编号

货号GTIN
63175-25MG-F04061832860473
63175-100MG-F04061832860466