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Merck
CN

66807

4,5-亚甲二氧基-1,2-苯二胺 二盐酸盐

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

别名:

1,2-二氨基-4,5-亚甲二氧基苯 二盐酸盐, 1,3-苯并二恶-5,6-二胺 二盐酸盐, 5,6-二氨基-1,3-苯并二氧杂环戊 二盐酸盐, MDB

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关于此项目

经验公式(希尔记法):
C7H8N2O2 · 2HCl
化学文摘社编号:
分子量:
225.07
UNSPSC Code:
12352111
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5641607
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产品名称

4,5-亚甲二氧基-1,2-苯二胺 二盐酸盐, BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

InChI

1S/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H

SMILES string

Cl[H].Cl[H].Nc1cc2OCOc2cc1N

InChI key

YXEJRYIEFFUUID-UHFFFAOYSA-N

product line

BioReagent

assay

≥97.0% (HPLC)

form

solid

Quality Level

mol wt

225.07 g/mol

concentration

≤100% (1,3-Benzodioxole-5,6-diamine hydrochloride (1:2))

color

white to faint red

mp

247-252 °C

fluorescence

λex 367 nm; λem 445 nm in 0.1 M phosphate pH 7.0 (after derivatization with pyruvate)

suitability

suitable for fluorescence

storage temp.

−20°C

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Application

用于测定α-酮酸的荧光试剂。

Disclaimer

可能会在存储期间褪色

General description

4,5-亚甲二氧基-1,2-苯二胺二盐酸盐是一种α酮酸的荧光标记。唾液酸衍生化也需要稀硫酸的存在作为必要条件。该方法可用于测定唾液酸。

Packaging

无底玻璃瓶。内容物在插入式融锥内。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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S Hara et al.
Analytical biochemistry, 164(1), 138-145 (1987-07-01)
A simple, rapid, and highly sensitive high-performance liquid chromatographic method is described for the determination of N-acetyl- and N-glycolylneuraminic acids in human and animal sera, glycoproteins, and glycolipids. The neuraminic acids, released by acid hydrolysis of these biological samples, are
Capillary Electrophoresis of Carbohydrates: From Monosaccharides to Complex Polysaccharides, 249-249 (2010)
Xiaoxiao Guo et al.
The Analyst, 145(13), 4512-4521 (2020-05-16)
The polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology available specifically optimised for identification and quantitative evaluation of potential
K Hamahashi et al.
Journal of tissue engineering and regenerative medicine, 9(1), 24-30 (2012-11-21)
The authors aimed to repair and regenerate articular cartilage with layered chondrocyte sheets, produced using temperature-responsive culture dishes. The purpose of this study was to investigate the humoral factors produced by layered chondrocyte sheets. Articular chondrocytes and synovial cells were
Antonietta Manna et al.
Brain and behavior, 5(7), e00334-e00334 (2015-07-30)
Deep brain gray matter (GM) structures are involved in several neurodegenerative disorders and are affected by aging. In this study, we investigated the potential relationship between levels of brain-derived neurotrophic factor (BDNF), a putative biomarker of age- and clinically relevant

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