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Merck
CN

69732

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

别名:

Lithium mupirocin solution, Li-MUP, MUP supplement

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关于此项目

经验公式（希尔记法）:
C26H43LiO9
化学文摘社编号:
73346-79-9
分子量:
506.56
NACRES:
NA.85
PubChem Substance ID:
329761909
UNSPSC Code:
41171614
MDL number:
MFCD11977847

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产品名称

Lithium mupirocin Supplement, suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

agency

ISO 29981:2010

sterility

sterile (Filtered and Aseptic Handled)
sterile

form

liquid

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

Quality Level

100

相关类别

Application

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

General description

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Other Notes

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM4587
BCCJ9097
BCCH6039
BCCH0638
BCCG6315

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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Kristin A Seiberling et al.
International forum of allergy & rhinology, 3(2), 94-98 (2012-11-30)
Antibiotic irrigations are occasionally used during endoscopic sinus surgery when gross mucosal infection is present. These irrigations are thought to flush out pathogenic bacteria and decrease the bacterial load within the mucosal surfaces. This treatment, however, has not been studied
Tomás García-Lozano et al.
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 25(4), 252-255 (2013-01-11)
Our objective was to determine the prevalence of methicillin-resistant Staphylococcus aureus in workers who had direct contact with oncologic patients infected with MRSA and admitted to the intensive care unit of the Valencian Institute of Oncology. A study of prevalence
Yi-Yuan Chiu et al.
BMC genomics, 13 Suppl 7, S21-S21 (2013-01-11)
To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often share similar local binding environments and motifs. As the exponential growth of
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