95162
2,3,5,6-四甲基吡嗪
analytical standard
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关于此项目
经验公式（希尔记法）:
C8H12N2
化学文摘社编号:
分子量:
136.19
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-391-2
Beilstein/REAXYS Number:
113100
MDL number:
产品名称
2,3,5,6-四甲基吡嗪, analytical standard
InChI
1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
SMILES string
Cc1nc(C)c(C)nc1C
InChI key
FINHMKGKINIASC-UHFFFAOYSA-N
grade
analytical standard
assay
≥98.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
bp
190 °C (lit.)
mp
77-80 °C (lit.)
85-87 °C
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
format
neat
Quality Level
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Application
2,3,5,6-四甲基吡嗪可用作分析参考标准品，用于通过不同的色谱技术对麻黄和草麻黄中的分析物进行定量。
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
General description
2,3,5,6-四甲基吡嗪是一种吡嗪类风味化合物。它是用于治疗哮喘的中药川芎和麻黄的主要活性成分。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Applications of Microbial Engineering (2013)
Analysis of tetramethylpyrazine in Ephedrae herba by gas chromatography?mass spectrometry and high-performance liquid chromatography
Lv K, et al.
Journal of Chromatography A, 878(1), 147-152 (2000)
Separation and determination of ephedrine alkaloids and tetramethylpyrazine in ephedra sinica Stapf by gas chromatography-mass spectrometry
Journal of Chromatographic Science, 39(9), 370-374 (2001)
Shouliang Wang et al.
Drug design, development and therapy, 13, 1187-1196 (2019-05-23)
Background: Bupivacaine (BUP) acts as a local anesthetic, which is extensively used for clinical patients but could generate neurotoxicity in neurons. Tetramethylpyrazine (TET) exhibits strong neuron protective effects against neurotoxicity. Hence, we investigate the effect of TET on BUP-induced neurotoxicity
Penglong Wang et al.
Die Pharmazie, 68(9), 782-789 (2013-10-24)
A new anticancer ligustrazine derivative, 3beta-hydroxyolea-12-en-28-oic acid-3,5,6-trimethylpyrazin-2-methyl ester (T-OA, C38H58O3N2), was previously reported. It was synthesized via conjugating the effective antitumor ingredients of a classic traditional Chinese medicine (TCM) formulation. In the present study, anticancer efficacy of T-OA was evaluated
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