96408
N-（2-苯乙酰基）甘氨酸
analytical standard
别名:
2-苯乙酰基甘氨酸, 2-（2-苯乙酰胺）乙酸, NSC 408424, NSC 92778, 苯乙酰甘氨酸, 苯乙酰脲酸
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关于此项目
经验公式（希尔记法）:
C10H11NO3
化学文摘社编号:
分子量:
193.20
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.24
Beilstein/REAXYS Number:
1107116
MDL number:
grade
analytical standard
Quality Level
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
application(s)
clinical testing
format
neat
storage temp.
2-8°C
SMILES string
N(CC(=O)O)C(=O)Cc1ccccc1
InChI
1S/C10H11NO3/c12-9(11-7-10(13)14)6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,12)(H,13,14)
InChI key
UTYVDVLMYQPLQB-UHFFFAOYSA-N
Biochem/physiol Actions
苯乙酰基甘氨酸是酰基甘氨酸。酰基甘氨酸通常是脂肪酸的次要代谢产物。但是，某些先天性代谢错误会增加某些酰基甘氨酸的排泄。在某些情况下，体液中这些代谢物的测量可用于诊断与线粒体脂肪酸β-氧化有关的疾病。酰基甘氨酸是通过甘氨酸N-酰基转移酶（EC 2.3.1.13）的作用产生的，甘氨酸N-酰基转移酶是一种催化化学反应的酶： 酰基辅酶A+甘氨酸 ↔ 辅酶A+N-酰基甘氨酸。苯乙酰甘氨酸或PAG是苯乙酸的甘氨酸偶联物。苯乙酸可能是由于暴露于苯乙烯（塑料）或通过食用水果和蔬菜而产生的。苯乙酸用于某些香水中，具有低浓度的蜂蜜样气味，也用于青霉素G的生产。PAG是磷脂沉着症的推定生物标记物。在许多组织中表现出异常磷脂积累的动物中，尿中PAG升高，因此可用作磷脂沉着症的替代生物标记物。已证实犬、大鼠和小鼠尿液中存在苯乙酰甘氨酸。但是，这种化合物在人尿中的存在是有争议的。GC-MS研究尚未发现该化合物，而NMR研究声称已鉴定出该化合物，但似乎苯乙酰基甘氨酸有时可能通过NMR被误认为苯乙酰基谷氨酰胺。
Other Notes
请在我们的在线平台NMR用请在我们的在线平台NMR用ChemisTwin®查找本产品的数字化标准物质。您可以利用ChemisTwin®上的数字化等效物质进行样品确认和化合物定量（采用数字化外标）。您可以查看该物质的NMR 谱，点击鼠标即可与您的样品在线比较。点击此处了解更多信息，并开始免费试用。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jane Delaney et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 9(3), 271-290 (2005-03-15)
Amiodarone was given to male Sprague-Dawley rats at a dose of 150 mg kg(-1) day(-1) for 7 consecutive days to induce phospholipidosis in the lungs of treated rats. Amiodarone was given alone or concurrently with phenobarbitone. Animals given amiodarone had
M Matsumoto et al.
The Journal of veterinary medical science, 57(2), 205-211 (1995-04-01)
After the urine was treated with urease, lyophilized, and trimethylsilylated, it was examined for metabolic profiles in Dalmatian dogs and Shetland sheepdogs by gas chromatography-mass spectrometry (GC/MS), which simultaneously analyzes organic acids, amino acids, sugars, sugar alcohols, purine and pyrimidine
Xiuting Yu et al.
Experimental and therapeutic medicine, 14(2), 1184-1192 (2017-08-16)
The incidence of inflammatory bowel disease (IBD), characterized by chronic, relapsing intestinal inflammation, has continually increased in recent years. A previous study by our group identified five potential metabolic markers possibly associated with the pathology of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced IBD
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 96408-10MG | 04061838445087 |
| 96408-250MG | 04061838445094 |
| 96408-50MG | 04061838445100 |