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经验公式(希尔记法):
C28H35FO7
化学文摘社编号:
分子量:
502.57
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
256-915-2
MDL number:
InChI key
ILKJAFIWWBXGDU-MOGDOJJUSA-N
InChI
1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1
SMILES string
[H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC6(CCCC6)O2)C(=O)COC(C)=O
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
Quality Level
Gene Information
human ... NR3C1(2908)
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General description
Amcinonide is a highly potent topical corticosteroid. It possesses pharmacological properties like anti-pruritic, anti-inflammatory and vasoconstrictive activity.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Mosby's Drug Reference for Health Professions null
Contact allergy to amcinonide.
Y Kubo et al.
Contact dermatitis, 15(2), 109-111 (1986-08-01)
B Berman et al.
Experimental cell research, 183(1), 215-228 (1989-07-01)
Serine protease inhibitors with a specificity for trypsin inhibit interferon-gamma (INF-gamma)-induced HLA-DR expression on a hybrid human epidermal cell line (H12), dermal fibroblasts, and primary keratinocytes. Protease inhibitors with a specificity for chymotrypsin or papain fail to inhibit IFN-gamma. The
Drugs for the Geriatric Patient E-Book: Text with BONUS Handheld Software (2007)
R Hayakawa et al.
Contact dermatitis, 12(4), 213-214 (1985-04-01)
Allergic contact dermatitis from topical corticosteroids has been regarded as rare. However, it should be considered in long-standing, resistant or worsening eczema in spite of topical steroid therapy. Cases of allergic dermatitis from amcinonide have been reported previously. We report
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