Merck
CN
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文件

A3648

Sigma-Aldrich

(3-氨基丙基)三乙氧基硅烷

≥98%

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别名:
APTS, 3-氨丙基三乙氧基硅烷, APTES
线性分子式:
H2N(CH2)3Si(OC2H5)3
CAS号:
919-30-2
分子量:
221.37
Beilstein:
1754988
EC 号:
213-048-4
MDL编号:
MFCD00008207
PubChem化学物质编号:
24890794
NACRES:
NA.47

质量水平

200

检测方案

≥98%

形式

liquid

pH值（酸碱度）

11 (20 °C, 20 g/L)

bp

217 °C/760 mmHg (lit.)

mp

220-222 °C

密度

0.946 g/mL at 25 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES string

CCO[Si](CCCN)(OCC)OCC

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

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相关类别

应用

  • （3-氨基丙基）三乙氧基硅烷已用于制备玻片上的钙粘蛋白表面。
  • 它已用于制备RGD（Arg-Gly-Asp）处理的有机硅膜。
  • 它已用于制备亲和素-生物素盖玻片。

生化/生理作用

（3-氨基丙基）三乙氧基硅烷可形成玻璃的氨基丙基衍生物，一种用于亲和色谱的吸附剂。它用于制备适合用于各种免疫组化和原位杂交过程的带正电荷的玻片。

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302 - H314 - H317

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

闪点(°F)

199.4 °F - closed cup

闪点(°C)

93 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

分析证书(COA)

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示例

T1503
货号
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25G
包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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索取COA

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. How does Product A3648, (3-Aminopropyl)triethoxysilane, compare to poly-L-lysine for binding tissue to glass surfaces?

    This product has been cited as being a better tissue adhesive than poly-L-lysine. Maddox PH, Jenkins D., 3-Aminopropyltriethoxysilane (APES): a new advance in section adhesion. J Clin Pathol., 40(10):1256-7 (1987).

  5. Can Product A3648, (3-Aminopropyl)triethoxysilane, be used to coat controlled pore glass?

    To coat controlled-pore glass beads for affinity chromatography, the following method is recommended:1. Treat 1 g of clean beads with 20 mL of a 10% aqueous A3648 (pH 3 to 4) at 75 °C for 2 hours.2. Filter the beads to remove the solution and dry overnight in a 115 °C oven. See: J. Dairy Sci., 73, 2720-2730 (1990).

  6. Can I buy glass slides already treated with Product A3648, (3-Aminopropyl)triethoxysilane?

    Yes. Silane Prep slides, Product No. S4651, are produced using A3648. These slides have an expiration period of 24 months.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

  8. What is the concentration of the (3-Aminopropyl)triethoxysilane, commonly known as APTES?

    The (3-Aminopropyl)triethoxysilane, which is a neat liquid, is 4.3 M. This is based on a density of 0.946 g/mL and a molecular weight of 221.37.

  9. Can the coating made from product A3648, (3-Aminopropyl)triethoxysilane, be removed?

    For Product A3648, (3-Aminopropyl)triethoxysilane, the siliconized coating can be removed by an overnight treatment with 10-20% (w/v) aqueous or alcoholic potassium hydroxide or sodium hydroxide solutions. It may also be possible to remove the coating by physical abrasion, i.e., scrubbing or vigorously brushing the glass surface. Autoclaving will not destroy the coating.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Real-time observation of a single DNA digestion by lambda exonuclease under a fluorescence microscope field.
Matsuura S, et al.
Nucleic Acids Research, 29, E79-E79 (2001)
Apoptosis and survival of osteoblast-like cells are regulated by surface attachment.
Grigoriou V, et al.
The Journal of Biological Chemistry, 280, 1733-1739 (2005)
Peng Yuan et al.
Nanotechnology, 23(37), 375705-375705 (2012-08-28)
The surfaces of naturally occurring halloysite nanotubes were functionalized with γ-aminopropyltriethoxysilane (APTES), which was found to have a substantial effect on the loading and subsequent release of a model dye molecule. APTES was mostly anchored at the internal lumen surface
H Delanoë-Ayari et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(8), 2229-2234 (2004-02-26)
Physicists have studied the aggregation of adhesive proteins, giving a central role to the elastic properties of membranes, whereas cell biologists have put the emphasis on the cytoskeleton. However, there is a dramatic lack of experimental studies probing both contributions
Isabelle Bonnet et al.
Nucleic acids research, 36(12), 4118-4127 (2008-06-12)
The restriction endonuclease EcoRV can rapidly locate a short recognition site within long non-cognate DNA using 'facilitated diffusion'. This process has long been attributed to a sliding mechanism, in which the enzyme first binds to the DNA via nonspecific interaction
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