form
solid
mol wt
~2163
color
white
solubility
H2O: soluble
application(s)
hematology
histology
storage temp.
−20°C
Quality Level
Application
ADVASEP™-7已被用于洗涤溶液中，以去除染色细胞中多余的染料（FM4-64FX和FM1-43）。
Biochem/physiol Actions
ADVASEP™-7是一种β-环糊精衍生物。它可以用作染料清除剂以及背景染料去除。
用SynaptoGreen减少质膜的背景染色™。
Other Notes
磺化的β-环糊精。NTSI、NTSII和NTSV的组成成分，亦可单独出售。
Legal Information
Advasep is a trademark of Cydex Pharmaceuticals, Inc.
SynaptoGreen is a trademark of Biotium, Inc.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A R Kay et al.
Neuron, 24(4), 809-817 (2000-01-07)
The fluorescent probe FM1-43 has been used extensively for imaging vesicle recycling; however, high nonspecific adsorption resulting in elevated background levels has precluded its use in certain tissues, notably brain slices. We have found that a sulfobutylated derivative of beta-cyclodextrin
The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype.
Hosseinibarkooie S, et al.
American Journal of Human Genetics, 99, 647-647 (2016)
Imaging synaptic vesicle exocytosis and endocytosis with FM dyes.
Gaffield MA and Betz WJ
Nature Protocols, 1, 2916-2916 (2006)
?-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.
Brown LE, et al.
The Journal of Biological Chemistry, 291, 13926-13926 (2016)
Samuel Lundt et al.
Scientific reports, 10(1), 99-99 (2020-01-11)
Nicotinamide adenine dinucleotide (NAD+) plays a critical role in energy metabolism and bioenergetic homeostasis. Most NAD+ in mammalian cells is synthesized via the NAD+ salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme, converting nicotinamide into nicotinamide mononucleotide (NMN).
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