产品名称
2-氨基联苯, ≥96.5% (GC)
蒸汽密度
5.8 (vs air)
质量水平
方案
≥96.5% (GC)
表单
powder or crystals
自燃温度
842 °F
技术
titration: suitable
杂质
<0.1% 4-aminobiphenyl
颜色
brown
off-white to yellow
沸点
299 °C (lit.)
mp
47-50 °C (lit.)
溶解性
water: insoluble
密度
1.16 g/cm3 at 21 °C
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
Nc1ccccc1-c2ccccc2
InChI
1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
InChI key
TWBPWBPGNQWFSJ-UHFFFAOYSA-N
基因信息
human ... UGT1A4(54657)
正在寻找类似产品? 访问 产品对比指南
一般描述
2-氨基联苯是UGT(UDP-葡糖醛酸转移酶)的底物,包括UGT1A4、UGT2B13和UGT2B16。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
307.4 °F - closed cup
闪点(°C)
153 °C - closed cup
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Uesawa Y, et al.
Drug Metabolism and Disposition, 32, 1476-1481 (2004)
Chien-Cheng Chen et al.
Chemical research in toxicology, 25(3), 695-705 (2012-02-01)
Overexposure to biphenyl amine compounds, which are found in smoke and azo-dyes, is linked to the occurrence of bladder cancer. However, the molecular mechanisms of biphenyl amine compound-induced bladder cancer are still unclear. Many studies have demonstrated that overexpression of
Gerald Pratsch et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(37), 11555-11559 (2012-08-14)
Simply aqueous sodium hydroxide is sufficient to exclude ionic side reactions and to prepare 2-aminobiphenyls from aryl diazotates and anilines through a new variant of the Gomberg-Bachmann reaction (see scheme). The metal-free reaction under basic conditions allows to exploit the
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持
