A42409
2-氨基联苯
≥96.5% purity, powder or crystals
别名:
2-联苯胺, 邻苯基苯胺
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关于此项目
线性分子式:
C6H5C6H4NH2
化学文摘社编号:
分子量:
169.22
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
201-990-9
MDL number:
Beilstein/REAXYS Number:
471874
产品名称
2-氨基联苯, ≥96.5% (GC)
vapor density
5.8 (vs air)
Quality Level
assay
≥96.5% (GC)
form
powder or crystals
autoignition temp.
842 °F
technique(s)
titration: suitable
impurities
<0.1% 4-aminobiphenyl
color
brown, off-white to yellow
bp
299 °C (lit.)
mp
47-50 °C (lit.)
solubility
water: insoluble
density
1.16 g/cm3 at 21 °C
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Nc1ccccc1-c2ccccc2
InChI
1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
InChI key
TWBPWBPGNQWFSJ-UHFFFAOYSA-N
Gene Information
human ... UGT1A4(54657)
General description
2-氨基联苯是UGT（UDP-葡糖醛酸转移酶）的底物，包括UGT1A4、UGT2B13和UGT2B16。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
307.4 °F - closed cup
flash_point_c
153 °C - closed cup
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Uesawa Y, et al.
Drug Metabolism and Disposition, 32, 1476-1481 (2004)
M M Marques et al.
Chemical research in toxicology, 3(6), 559-565 (1990-11-01)
The complementary pentadecamers d(5'-TACTCTTCTTGACCT) (strand A) and d(5'-AGGTCAAGAAGAGTA) (strand B), which span a portion of the mouse c-Ha-ras protooncogene centered around codon 61, were synthesized by using standard beta-cyanoethyl phosphoramidite chemistry and characterized by sequence analysis. Strand A, containing a
Thin layer chromatographic separation and fluorometric determination of 4-aminobiphenyl in 2-aminobiphenyl.
J Zynger et al.
IARC scientific publications, (40)(40), 229-233 (1981-01-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A42409-25G | 04061833368626 |
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