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线性分子式:
C6H5C6H4NH2
化学文摘社编号:
分子量:
169.22
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
201-990-9
MDL number:
Beilstein/REAXYS Number:
471874
产品名称
2-氨基联苯, ≥96.5% (GC)
InChI
1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
InChI key
TWBPWBPGNQWFSJ-UHFFFAOYSA-N
SMILES string
Nc1ccccc1-c2ccccc2
vapor density
5.8 (vs air)
assay
≥96.5% (GC)
form
powder or crystals
autoignition temp.
842 °F
technique(s)
titration: suitable
impurities
<0.1% 4-aminobiphenyl
color
brown, off-white to yellow
bp
299 °C (lit.)
mp
47-50 °C (lit.)
solubility
water: insoluble
density
1.16 g/cm3 at 21 °C
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
Gene Information
human ... UGT1A4(54657)
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General description
2-氨基联苯是UGT(UDP-葡糖醛酸转移酶)的底物,包括UGT1A4、UGT2B13和UGT2B16。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
307.4 °F - closed cup
flash_point_c
153 °C - closed cup
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
M M Marques et al.
Chemical research in toxicology, 3(6), 559-565 (1990-11-01)
The complementary pentadecamers d(5'-TACTCTTCTTGACCT) (strand A) and d(5'-AGGTCAAGAAGAGTA) (strand B), which span a portion of the mouse c-Ha-ras protooncogene centered around codon 61, were synthesized by using standard beta-cyanoethyl phosphoramidite chemistry and characterized by sequence analysis. Strand A, containing a
Thin layer chromatographic separation and fluorometric determination of 4-aminobiphenyl in 2-aminobiphenyl.
J Zynger et al.
IARC scientific publications, (40)(40), 229-233 (1981-01-01)
Gerald Pratsch et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(37), 11555-11559 (2012-08-14)
Simply aqueous sodium hydroxide is sufficient to exclude ionic side reactions and to prepare 2-aminobiphenyls from aryl diazotates and anilines through a new variant of the Gomberg-Bachmann reaction (see scheme). The metal-free reaction under basic conditions allows to exploit the
High-performance liquid chromatography with on-line radioactivity monitoring for metabolic studies of 2- and 4-[14C]aminobiphenyls.
S D Jatoe et al.
Journal of chromatography, 442, 394-400 (1988-06-17)
Agricultural and Biological Chemistry, 38, 1209-1209 (1974)
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