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Merck
CN

B1145000

溴己新 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

2-氨基-3,5-二溴-N-环己基-N-甲基苄胺 盐酸盐, N-(2-氨基-3,5-二溴苄基)-N-甲基环己胺 盐酸盐, 溴苄环己铵 盐酸盐

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关于此项目

经验公式(希尔记法):
C14H20Br2N2 · HCl
化学文摘社编号:
分子量:
412.59
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4848376
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grade

pharmaceutical primary standard

API family

bromhexine

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

InChI key

UCDKONUHZNTQPY-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bromhexine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mladen Stojanov et al.
International journal of pharmaceutics, 422(1-2), 349-355 (2011-10-27)
Bromhexine hydrochloride (bromhexine) is a mucolytic agent with very low aqueous solubility. However, with addition of cyclodextrins (CD) to the formulation, this disadvantage may be limited and therapeutic doses of bromhexine in solution can be achieved. The interaction of bromhexine
Matthew E Spector et al.
Head & neck, 34(12), 1727-1733 (2012-01-17)
Despite better prognosis, there is a group of oropharyngeal squamous cell carcinoma (SCC) human papillomavirus (HPV)+ patients who experience treatment failure and succumb to distant metastasis. Seventy-eight previously untreated patients nested in a concurrent chemoradiation protocol were reviewed to correlate
Saman Azodi-Deilami et al.
Applied biochemistry and biotechnology, 164(2), 133-147 (2010-11-16)
Imprinted polymers are now being increasingly considered for active biomedical uses such as drug delivery. In this work, the use of molecularly imprinted polymers (MIPs) in designing new drug delivery devices was studied. Imprinted polymers were prepared from methacrylic acid



全球贸易项目编号

货号GTIN
B114500004061833421154