所有图片(2)
About This Item
经验公式（希尔记法）:
C10H11BrN2O2
CAS号:
分子量:
271.11
Beilstein:
4430959
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
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产品名称
溴乙烷, ≥97% (HPLC)
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
yellow
mp
161 °C
溶解性
acetonitrile: 20 mg/mL
ε (消光系数)
4.6-5.1 at 396-398 nm in H2O
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
CC1=C(C)C(=O)N2N1C(CBr)=C(C)C2=O
InChI
1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
InChI key
AHEWZZJEDQVLOP-UHFFFAOYSA-N
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一般描述
溴代双满又称单溴联苯胺。它还是一种已知的硫醇探针，是一种在光解反应后活化的荧光试剂。
应用
溴代双满用于高效液相色谱法硫醇测定,适于荧光测定2，3-二巯基丙烷-1-磺酸和其他二硫醇。溴代双满已用作研究牛心线粒体寡霉素敏感性 ATP 酶的荧光标记。
此物质可用于体内和体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。
此物质可用于体内和体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。
生化/生理作用
溶液形式的溴代双满可与小分子硫醇基（如 GSH）和反应性蛋白硫醇基（如血红蛋白）反应。溴代双满与硫醇的反应为二级pH依赖性反应，且在与硫醇盐反应后，可活化水溶性荧光产物以便检测。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
N S Kosower et al.
Proceedings of the National Academy of Sciences of the United States of America, 76(7), 3382-3386 (1979-07-01)
The bimane fluorescent labels, monobromobimane, dibromobimane, and monobromotrimethylammoniobimane, are derivatives of syn-9,10-dioxabimane:1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-dione. They efficiently label hemoglobin (reactive thiol groups), membrane proteins, and glutathione of normal human red cells under physiological conditions. Monobromobimane and dibromobimane are effective on intact cells while
Differing effects of mechanical dough development and sheeting development methods on aggregated glutenin proteins.
Sutton KH, et al.
Cereal Chem., 80.6, 707-711 (2003)
Xiao Jie Yao et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(23), 9501-9506 (2009-05-28)
G protein-coupled receptors (GPCRs) mediate the majority of physiologic responses to hormones and neurotransmitters. However, many GPCRs exhibit varying degrees of agonist-independent G protein activation. This phenomenon is referred to as basal or constitutive activity. For many of these GPCRs
Edward A Wintner et al.
British journal of pharmacology, 160(4), 941-957 (2010-07-02)
Hydrogen sulphide (H(2)S) is a labile, endogenous metabolite of cysteine, with multiple biological roles. The development of sulphide-based therapies for human diseases will benefit from a reliable method of quantifying H(2)S in blood and tissues. Concentrations of reactive sulphide in
Bromobimane probes for thiols.
E M Kosower et al.
Methods in enzymology, 251, 133-148 (1995-01-01)
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