产品名称
7H-二苯并[c,g]咔唑, BCR®, certified reference material
InChI key
STJXCDGCXVZHDU-UHFFFAOYSA-N
SMILES string
[H]n1c2ccc3ccccc3c2c4c1ccc5ccccc45
InChI
1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H
grade
certified reference material
agency
BCR®
manufacturer/tradename
JRC
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
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Analysis Note
For more information please see:
BCR266
BCR266
Legal Information
BCR is a registered trademark of European Commission
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Glenn Talaska et al.
Toxicology letters, 162(2-3), 246-249 (2005-11-01)
Studies of the impact of phase 1 enzyme polymorphisms on genetic damage have yielded mixed results. We studied how genetic damage would be altered when specific genes were ablated under low dose conditions. Knockouts (KO) were generated from c57bl6/J mice
Zuzana Valovicová et al.
Mutation research, 665(1-2), 51-60 (2009-05-12)
Liver progenitor (oval) cells are a potential target cell population for hepatocarcinogens. Our recent study showed that the liver carcinogens 7H-dibenzo[c,g]carbazole (DBC) and 5,9-dimethyldibenzo[c,g]carbazole (DiMeDBC), but not the sarcomagen N-methyldibenzo[c,g]carbazole (N-MeDBC), induced several cellular events associated with tumor promotion in
O Dorchies et al.
Toxicologic pathology, 29(5), 528-534 (2001-11-07)
The purpose of this work was to investigate the administration of very low but repeated doses of a genotoxic carcinogen and an eventual correlation with cellular DNA synthesis. The compound 7H-dibenzo[c,g]carbazole is a genotoxic carcinogen in the mouse liver and
G Ericson et al.
Mutation research, 454(1-2), 11-20 (2000-10-18)
The time-course and dose dependent formation of DNA adducts in juvenile northern pike (Esox lucius) following a single exposure to a mixture of benzo[a]pyrene (BaP), benzo[k]fluoranthene (BkF) and 7H-dibenzo[c,g]carbazole (DBC) were investigated by use of the (32)P-postlabelling assay. A complex
Alena Gábelová et al.
Environmental and molecular mutagenesis, 52(8), 636-645 (2011-08-03)
The goal of this study was to investigate the genotoxicity of 7H-dibenzo[c,g]carbazole (DBC), a ubiquitous environmental pollutant, and its methyl derivatives, 5,9-dimethylDBC (DiMeDBC), a strict hepatocarcinogen, and N-methylDBC (N-MeDBC), a specific sarcomagen in human hepatoma HepG2 cells, and to infer
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