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Merck
CN

BP464

泼尼松龙

British Pharmacopoeia (BP) Assay Standard

别名:

1,4-孕甾二烯-11β,17α,21-三醇-3,20-二酮, 1-去氢氢化可的松, 1-去氢皮质醇, 11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮

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关于此项目

经验公式（希尔记法）:
C21H28O5
化学文摘社编号:
50-24-8
分子量:
360.44
Beilstein:
1354103
EC 号:
200-021-7
MDL编号:
MFCD00003649
UNSPSC代码:
41116107
NACRES:
NA.24

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等级

pharmaceutical primary standard

API类

prednisolone

表单

crystalline

保质期

limited shelf life, expiry date on the label

制造商/商品名称

BP

mp

240 °C (dec.) (lit.)

应用

pharmaceutical
pharmaceutical small molecule

包装形式

neat

SMILES字符串

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

OIGNJSKKLXVSLS-VWUMJDOOSA-N

基因信息

human ... NR3C1(2908)

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Prednisolone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Estriol Cream
  • Prednisolone Sodium Phosphate Ear Drops
  • Prednisolone Sodium Phosphate Eye Drops
  • Prednisolone Tablets
  • Prednisolone Soluble Tablets
  • Prednisolone Enema
  • Prednisolone Sodium Phosphate Oral Solution
  • Prednisolone Gastro-resistant Tablets

    • 其他说明

    Sales restrictions may apply.

    象形图

    Health hazard
    GHS08

    警示用语：

    Danger

    危险声明

    H360FD

    危险分类

    Repr. 1B

    储存分类代码

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 2

    法规信息

    涉药品监管产品
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    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Eng Cern Gan et al.
    International forum of allergy & rhinology, 4(11), 877-884 (2014-08-20)
    The endoscopically magnified operative field in functional endoscopic sinus surgery (FESS) makes even a small amount of bleeding a potentially significant hindrance. It is thought that irrigation with hot saline during surgery may improve surgical field of view by producing
    Carolien Out et al.
    Journal of hepatology, 61(2), 351-357 (2014-04-01)
    Glucocorticoids, produced by the adrenal gland under control of the hypothalamic-pituitary-adrenal axis, exert their metabolic actions largely via activation of the glucocorticoid receptor (GR). Synthetic glucocorticoids are widely used as anti-inflammatory and immunosuppressive drugs but their application is hampered by
    Ramachandran Venkitaraman et al.
    European urology, 67(4), 673-679 (2014-12-03)
    Prednisolone is widely used as secondary hormonal treatment for castration-resistant prostate cancer (CRPC). We hypothesised that dexamethasone, another corticosteroid, is more active. To compare the activity of prednisolone and dexamethasone in CRPC. This single-centre, randomised, phase 2 trial was performed
    T Bakchoul et al.
    Journal of thrombosis and haemostasis : JTH, 12(6), 871-878 (2014-03-25)
    Heparin, the standard perioperative anticoagulant for the prevention of graft vessel thrombosis in patients undergoing liver transplantation (LT), binds to the chemokine platelet factor 4 (PF4). Antibodies that are formed against the resulting PF4/heparin complexes can induce heparin-induced thrombocytopenia. LT
    C Motteram et al.
    Reproductive biomedicine online, 30(4), 340-348 (2015-02-14)
    The effectiveness of combined co-treatment with aspirin, doxycycline, prednisolone, with or without oestradiol patches, was investigated on live birth (LBR) rates after fresh and frozen embryo transfers (FET) in IVF and intracytoplasmic sperm injection cycles. Cases (n = 485) and
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