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C2734

5-羧基四甲基罗丹明

Name: 5-羧基四甲基罗丹明
Brand: SIAL

≥95% purity (HPLC), solid

别名:

5-TAMRA

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关于此项目

经验公式（希尔记法）:

C₂₅H₂₂N₂O₅

化学文摘社编号:

91809-66-4

分子量:

430.45

UNSPSC Code:

12171500

NACRES:

NA.47

MDL number:

MFCD01073638

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属性

产品名称

5-羧基四甲基罗丹明,

assay

≥95% (HPLC)

Quality Level

100

form

solid

solubility

water: slightly soluble

ε (extinction coefficient)

≥85000-97000 at 539-545 nm in methanol

fluorescence

λ_ex ~543 nm; λ_em ~570 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

N(C)(C)c1cc2[o+]c3c(c(c2cc1)c4c(cc(cc4)C(=O)[O-])C(=O)O)ccc(c3)N(C)C

InChI

1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)

InChI key

YMZMTOFQCVHHFB-UHFFFAOYSA-N

说明

General description

在高纯度中制备的重要荧光基团，通过约 600 个分子的毛细管电泳检测限为 TMR 标记氨基酸。容易被荧光显微镜中使用的汞弧灯的 546 nm 光谱线激发，本质上比荧光素更具光稳定性。

Application

5-羧基四甲基罗丹明已用于荧光团表征。

Biochem/physiol Actions

5-羧基四甲基罗丹明可以共价连接到 DNA 上，从而用于涉及分支和双链 DNA/RNA 结构的研究。主要用于单分子研究。5-羧基四甲基罗丹明也用于标记寡糖，用于激光诱导荧光检测。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pimenta S, et al.

Journal of Biomedical Optics, 23(10), 105004-105004 (2018)

Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside-RNA hairpin loop interactions.

Dustin J Paul et al.

Nucleic acids research, 37(17), 5894-5907 (2009-09-04)

Herein, we report the identification of RNA hairpin loops that bind derivatives of kanamycin A, tobramycin, neamine, and neomycin B via two-dimensional combinatorial screening, a method that screens chemical and RNA spaces simultaneously. An arrayed aminoglycoside library was probed for

mRNA localization, reaction centre biogenesis and thylakoid membrane targeting in cyanobacteria.

Moontaha Mahbub et al.

Nature plants, 6(9), 1179-1191 (2020-09-09)

The thylakoid membranes of cyanobacteria form a complex intracellular membrane system with a distinctive proteome. The sites of biogenesis of thylakoid proteins remain uncertain, as do the signals that direct thylakoid membrane-integral proteins to the thylakoids rather than to the

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全球贸易项目编号

货号	GTIN
C2734-10MG	04061832341941