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Merck
CN

C2734

Sigma-Aldrich

5-羧基四甲基罗丹明

≥95% purity (HPLC), solid

别名:

5-TAMRA

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About This Item

经验公式(希尔记法):
C25H22N2O5
CAS号:
分子量:
430.45
MDL编号:
UNSPSC代码:
12171500
NACRES:
NA.47

product name

5-羧基四甲基罗丹明,

检测方案

≥95% (HPLC)

质量水平

形式

solid

溶解性

water: slightly soluble

ε (消光系数)

≥85000-97000 at 539-545 nm in methanol

荧光

λex ~543 nm; λem ~570 nm in methanol

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

InChI

1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)

InChI key

YMZMTOFQCVHHFB-UHFFFAOYSA-N

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一般描述

在高纯度中制备的重要荧光基团,通过约 600 个分子的毛细管电泳检测限为 TMR 标记氨基酸。容易被荧光显微镜中使用的汞弧灯的 546 nm 光谱线激发,本质上比荧光素更具光稳定性。

应用

5-羧基四甲基罗丹明已用于荧光团表征。

生化/生理作用

5-羧基四甲基罗丹明可以共价连接到 DNA 上,从而用于涉及分支和双链 DNA/RNA 结构的研究。主要用于单分子研究。5-羧基四甲基罗丹明也用于标记寡糖,用于激光诱导荧光检测。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Dustin J Paul et al.
Nucleic acids research, 37(17), 5894-5907 (2009-09-04)
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Journal of Biomedical Optics, 23(10), 105004-105004 (2018)
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ACS applied materials & interfaces, 9(46), 40059-40069 (2017-10-13)
Iron oxide nanostructures have been widely developed for biomedical applications because of their magnetic properties and biocompatibility. In clinical applications, stabilization of these nanostructures against aggregation and nonspecific interactions is typically achieved using weakly anchored polysaccharides, with better-defined and more
Limary M Cancel et al.
Scientific reports, 8(1), 9265-9265 (2018-06-20)
We investigated the effects of direct current stimulation (DCS) on fluid and solute transport across endothelial cell (EC) monolayers in vitro. Our motivation was transcranial direct current stimulation (tDCS) that has been investigated for treatment of neuropsychiatric disorders, to enhance
Rafal P Piprek et al.
Developmental biology, 432(2), 298-310 (2017-10-31)
Information on the mechanisms orchestrating sexual differentiation of the bipotential gonads into testes or ovaries in amphibians is limited. The aim of this study was to investigate the development of Xenopus laevis gonad, to identify the earliest signs of sexual

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