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文件

D2600000

苯海拉明盐酸盐

Name: 苯海拉明 盐酸盐
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

2-二苯基甲氧基- N , N -二甲基乙胺盐酸盐, N -（2-二苯基甲氧基乙基）- N , N -二甲胺盐酸盐

经验公式（希尔记法）:

C₁₇H₂₁NO · HCl

CAS号:

147-24-0

分子量:

291.82

MDL编号:

MFCD00012479

PubChem化学物质编号:

329798746

NACRES:

NA.24

等级

pharmaceutical primary standard

API family

diphenhydramine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

格式

neat

SMILES string

Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key

PCHPORCSPXIHLZ-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Diphenhydramine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

PHR1899

PHR1897

苯海拉明杂质B, Pharmaceutical Secondary Standard; Certified Reference Material

BP896

苯海拉明盐酸盐, British Pharmacopoeia (BP) Reference Standard

PHR1898

盐酸苯海拉明氧化物, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1993

PHR2071

苯海拉明杂质D, Pharmaceutical Secondary Standard; Certified Reference Material

BP1119

二苯甲醇, British Pharmacopoeia (BP) Reference Standard

PHR2268

Diphenhydramine Citrate, pharmaceutical secondary standard, certified reference material

象形图

GHS07

警示用语：

Warning

危险声明

H302

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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索取COA

Acetaminophen/diphenhydramine overdose in profound hypothermia.

A D Rollstin et al.

Clinical toxicology (Philadelphia, Pa.), 51(1), 50-53 (2012-12-01)

There are few reports of acetaminophen overdose in hypothermic patients and even fewer reports describing profound hypothermia. The kinetics, risk of hepatotoxicity, and the possible dose adjustments to N-acetylcysteine (NAC) therapy are not known in this setting. A 37-year-old female

The antihistamine diphenhydramine is extremely persistent in agricultural soil.

Edward Topp et al.

The Science of the total environment, 439, 136-140 (2012-10-16)

The widely used antihistamine diphenhydramine is present in municipal biosolids, and is detected in runoff from agricultural land fertilized with biosolids. In the present study the kinetics and major pathways of diphenhydramine dissipation in a loam, sandy loam, and clay

Changing patterns of drug and alcohol use in fatally injured drivers in Washington State.

Eugene W Schwilke et al.

Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)

We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens

Human genome-guided identification of memory-modulating drugs.

Andreas Papassotiropoulos et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(46), E4369-E4374 (2013-10-23)

In the last decade there has been an exponential increase in knowledge about the genetic basis of complex human traits, including neuropsychiatric disorders. It is not clear, however, to what extent this knowledge can be used as a starting point

Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors.

Don W Coulter et al.

Anti-cancer drugs, 24(4), 415-421 (2013-01-19)

A pediatric study has established a maximum tolerated dose (MTD) for temsirolimus (Tem) of more than 150 mg/m intravenously/week. A phase I trial was conducted to establish the MTD for Tem in combination with valproic acid (VPA) in children and

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苯海拉明 盐酸盐