biological source
bacterial (Leuconostoc mesenteroides)
Quality Level
form
powder
optical activity
[α]/D 90 to 105 °, c = 6% (w/v) in water
mol wt
average mol wt >500,000 (dextran starting material)
contains
0.5-2.0% phosphate buffer, pH 6-8
composition
Sulfur Content, 16.0-19.0%
color
white to off-white
useful pH range
6.0-8.0 (1% in water)
solubility
H2O: 100 mg/mL
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General description
硫酸葡聚糖是带负电荷的硫酸化多糖， 可由葡聚糖与氯磺酸的酯化反应产生。具有抗病毒、抗凝血和佐剂特性。葡聚糖用于治疗出血、烧伤、手术伤口和创伤。可以增加血流量，阻断红细胞聚集。葡聚糖降低血栓形成和术后肺栓塞风险。作为核糖核酸酶抑制剂发挥作用。
Application
从明串珠菌属某些种（Leuconostoc spp）中提取的硫酸葡聚糖钠盐可用于：
- 使含脂肪的血浆脱脂（67）（70）
- 诱发啮齿类动物远端结肠发生炎症和致癌反应（68）
- 制备3,4-乙撑二氧噻吩（EDOT）（69）
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
PEDOT doped with algal, mammalian and synthetic dopants: polymer properties, protein and cell interactions, and influence of electrical stimulation on neuronal cell differentiation
Molino PJ, et al.
Biomaterials Science, 6(5), 1250-1261 (2018)
The Molecular Biology of Poliovirus (2012)
Julien Charest et al.
Developmental cell, 55(4), 483-499 (2020-10-02)
Combinatorial action of transcription factors (TFs) with partially overlapping expression is a widespread strategy to generate novel gene-expression patterns and, thus, cellular diversity. Known mechanisms underlying combinatorial activity require co-expression of TFs within the same cell. Here, we describe the
Delipidation of plasma has minimal effects on human butyrylcholinesterase
Onder S, et al.
Frontiers in Pharmacology, 9, 117-117 (2018)
Zora Djuric et al.
The Journal of nutritional biochemistry, 46, 90-99 (2017-05-10)
Dietary fish oils have potential for prevention of colon cancer, and yet the mechanisms of action in normal and tumor colon tissues are not well defined. Here we evaluated the impact of the colonic fatty acid milieu on the formation
实验方案
Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.
硫酸葡聚糖以钠盐形式供应，使其在水中可溶且稳定。硫酸葡聚糖含有大约17%的硫，相当于每个葡糖基残基大约有2.3个硫酸基团。
相关内容
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D6001-50G | 04061833033142 |
| D6001-500G | 04061833587157 |
| D6001-100G | 04061833587126 |
| D6001-1G | 04061833587140 |
| D6001-10G | 04061833587133 |
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