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Merck
CN

E3257

乙二醇-双(琥珀酸 N-羟基琥珀酰亚胺酯)

powder

别名:

EGS, 乙二醇二琥珀酸二(N-琥珀酰亚胺基)酯, 乙二醇双(琥珀酰亚胺琥珀酸酯), 二(N-琥珀酰亚胺基)乙二醇二琥珀酸酯

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关于此项目

经验公式(希尔记法):
C18H20N2O12
化学文摘社编号:
分子量:
456.36
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
9167119
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form

powder

Quality Level

reaction suitability

reagent type: cross-linking reagent

color

white to off-white

solubility

DMF: soluble, acetic acid: water (1:1): ≤50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

O=C(CCC(=O)ON1C(=O)CCC1=O)OCCOC(=O)CCC(=O)ON2C(=O)CCC2=O

InChI

1S/C18H20N2O12/c21-11-1-2-12(22)19(11)31-17(27)7-5-15(25)29-9-10-30-16(26)6-8-18(28)32-20-13(23)3-4-14(20)24/h1-10H2

InChI key

QLHLYJHNOCILIT-UHFFFAOYSA-N

Application

乙二醇-双(琥珀酸 N -羟基琥珀酰亚胺酯)已被用作交联剂。

Biochem/physiol Actions

乙二醇-双(琥珀酸 N-羟基琥珀酰亚胺酯)是一种同双功能、可裂解交联剂。 主要通过 pH 值为7.5 的(6.5-8.5) 缓冲的酰胺键与含有伯胺的分子偶联。该连接提供了 12 个原子的间隔区。

Features and Benefits

乙二醇键可被羟胺裂解。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jin-Woo Yang et al.
Scientific reports, 7(1), 8060-8060 (2017-08-16)
Plant homeodomain finger protein 20 (PHF20), a methyl lysine effector protein, is a component MOF-NSL lysine acetyltranferase complex. Global deletion of PHF20 has shown spinal bone defects and reduced skeletal formation. However, the molecular basis of PHF20 involved in skeletal
Evgeniy V Petrotchenko et al.
Molecular & cellular proteomics : MCP, 4(8), 1167-1179 (2005-05-20)
An emerging approach for studying protein-protein interaction in complexes is the combination of chemical cross-linking and mass spectrometric analysis of the cross-linked peptides (cross-links) obtained after proteolysis of the complex. This approach, however, has several challenges and limitations, including the
Angela M Ingraham et al.
Annals of surgery, 270(2), 270-280 (2018-04-03)
To examine national adherence to emergency general surgery (EGS) best practices. There is a national crisis in access to high-quality care for general surgery emergencies. Acute care surgery (ACS), a specialty leveraging strengths of trauma systems, may ameliorate this crisis.



全球贸易项目编号

货号GTIN
E3257-250MG04061832346489
E3257-1G04061826116739