E3257
乙二醇-双（琥珀酸 N-羟基琥珀酰亚胺酯）
powder
别名:
EGS, 乙二醇二琥珀酸二（N-琥珀酰亚胺基）酯, 乙二醇双（琥珀酰亚胺琥珀酸酯）, 二（N-琥珀酰亚胺基）乙二醇二琥珀酸酯
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关于此项目
经验公式（希尔记法）:
C18H20N2O12
化学文摘社编号:
分子量:
456.36
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
9167119
产品名称
乙二醇-双（琥珀酸 N-羟基琥珀酰亚胺酯）, powder
solubility
DMF: soluble
acetic acid: water (1:1): ≤50 mg/mL
InChI
1S/C18H20N2O12/c21-11-1-2-12(22)19(11)31-17(27)7-5-15(25)29-9-10-30-16(26)6-8-18(28)32-20-13(23)3-4-14(20)24/h1-10H2
SMILES string
O=C(CCC(=O)ON1C(=O)CCC1=O)OCCOC(=O)CCC(=O)ON2C(=O)CCC2=O
InChI key
QLHLYJHNOCILIT-UHFFFAOYSA-N
form
powder
reaction suitability
reagent type: cross-linking reagent
color
white to off-white
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
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Application
乙二醇-双（琥珀酸 N -羟基琥珀酰亚胺酯）已被用作交联剂。
Biochem/physiol Actions
乙二醇-双（琥珀酸 N-羟基琥珀酰亚胺酯）是一种同双功能、可裂解交联剂。 主要通过 pH 值为7.5 的(6.5-8.5) 缓冲的酰胺键与含有伯胺的分子偶联。该连接提供了 12 个原子的间隔区。
Features and Benefits
乙二醇键可被羟胺裂解。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Angela M Ingraham et al.
Annals of surgery, 270(2), 270-280 (2018-04-03)
To examine national adherence to emergency general surgery (EGS) best practices. There is a national crisis in access to high-quality care for general surgery emergencies. Acute care surgery (ACS), a specialty leveraging strengths of trauma systems, may ameliorate this crisis.
Jin-Woo Yang et al.
Scientific reports, 7(1), 8060-8060 (2017-08-16)
Plant homeodomain finger protein 20 (PHF20), a methyl lysine effector protein, is a component MOF-NSL lysine acetyltranferase complex. Global deletion of PHF20 has shown spinal bone defects and reduced skeletal formation. However, the molecular basis of PHF20 involved in skeletal
Da Lin et al.
Nature genetics, 50(5), 754-763 (2018-04-28)
Chromosome conformation capture (3C) technologies can be used to investigate 3D genomic structures. However, high background noise, high costs, and a lack of straightforward noise evaluation in current methods impede the advancement of 3D genomic research. Here we developed a
Evgeniy V Petrotchenko et al.
Molecular & cellular proteomics : MCP, 4(8), 1167-1179 (2005-05-20)
An emerging approach for studying protein-protein interaction in complexes is the combination of chemical cross-linking and mass spectrometric analysis of the cross-linked peptides (cross-links) obtained after proteolysis of the complex. This approach, however, has several challenges and limitations, including the
Michael W Wandling et al.
The journal of trauma and acute care surgery, 83(5), 837-845 (2017-10-27)
Patients managed nonoperatively have been excluded from risk-adjusted benchmarking programs, including the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP). Consequently, optimal performance evaluation is not possible for specialties like emergency general surgery (EGS) where nonoperative management
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