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Merck
CN

E9884

乙二胺四乙酸

ACS reagent, 99.4-100.6%, powder

别名:

EDTA, Ethylenedinitrilotetraacetic acid, 亚乙基二次氮基四乙酸, 依地酸

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关于此项目

线性分子式:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
化学文摘社编号:
分子量:
292.24
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
39030907
UNSPSC Code:
12352106
EC Number:
200-449-4
MDL number:
Beilstein/REAXYS Number:
1716295
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产品名称

乙二胺四乙酸, ACS reagent, 99.4-100.6%, powder

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

grade

ACS reagent

agency

suitable for SM 4500 - NH3

assay

99.4-100.6%

form

powder

reaction suitability

reagent type: chelator

impurities

≤0.005% insoluble matter
≤0.1% Nitrilotriacetic acid ([HOCOCH2]3N)

ign. residue

≤0.2%

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

solubility

water: soluble 0.4 g/L at 20 °C

cation traces

Ca: ≤0.001%
Fe: ≤0.005%
Mg: ≤5 ppm
heavy metals: ≤0.001% (byICP-OES)

Quality Level

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Application

乙二胺四乙酸可用作:
  • 可用作标记缓冲液组分,在细胞裂解{155)过程中用于冲洗
  • 调查木瓜酶酵素对于伤口清创和其他皮肤问题的效果
  • 预处理之后,流式细胞仪收获大鼠血管平滑肌细胞

Biochem/physiol Actions

乙二胺四乙酸(EDTA)无法被胃肠道吸收。EDTA钠静脉注射导致低血钙手足抽搐。它通常用于血浆或分子诊断,和钙鳌合。EDTA可用作血液细胞计数和细胞形态分析中抗凝聚剂。

General description

乙二胺四乙酸(EDTA)是一种亲水金子螯合剂,将金属离子转化成无活性,环化金属复合物。因此,它在工业中可以用于解决金属污染物。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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分析证书(COA)

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CRC Desk Reference of Clinical Pharmacology, 215-215 (1997)
Henry's Clinical Diagnosis and Management by Laboratory Methods E-book, 28-28 (2011)
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Yaakobi T, et al.
Wounds : a compendium of clinical research and practice, 16, 201-205 (2004)
Adsorption of metal-ethylenediaminetetraacetic acid chelates onto lake sediment
Sillanpaa M and Ramo J
Chemosphere, 45, 881-885 (2001)
Renée S Suen et al.
The American journal of pathology, 179(3), 1549-1559 (2011-07-02)
Because both endothelin-1 (ET-1) and angiotensin II (AngII) are independent mediators of arterial remodeling, we sought to determine the role of ET receptor inhibition in AngII-accelerated atherosclerosis and aortic aneurysm formation. We administered saline or AngII and/or bosentan, an endothelin

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可生成组织和干细胞来源3D脑、胃肠道、肺和癌症肿瘤类器官模型的类器官培养产品。

实验方案

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