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Merck
CN

H0800000

Homatropine hydrobromide

European Pharmacopoeia (EP) Reference Standard

别名:

DL-Homatropine hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide, Tropine mandelate hydrobromide

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经验公式(希尔记法):
C16H21NO3 · HBr
化学文摘社编号:
分子量:
356.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

SMILES string

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI key

DWSGTFTVBLXELC-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

homatropine

manufacturer/tradename

EDQM

mp

214-217 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Amol Tamhane et al.
Ophthalmology, 112(11), 1963-1969 (2005-10-04)
To evaluate the role of amniotic membrane transplantation (AMT) in acute ocular burns. Prospective, randomized, controlled clinical trial. Patients with grade II to IV ocular burns within 3 weeks of injury were recruited. Thirty-seven patients, 7 of whom had bilateral
Elizabeth Hanno et al.
Optometry (St. Louis, Mo.), 80(2), 70-75 (2009-02-04)
Bilateral, recurrent, or chronic anterior uveitis requires a diagnostic evaluation to rule out any systemic cause. An understanding of the possible etiologies and their diagnostic criteria is needed to manage these patients. Treating any systemic cause can decrease the recurrent
Brian M Thome et al.
Journal of chromatography. A, 1138(1-2), 291-300 (2006-11-14)
Over the past decade the moving bed process has become a commonly used tool for the continuous separation of chiral compounds, and its recent application to electrophoretic separations allows the technique to be used as a model system for moving
Homatropine and psychosis in Weill-Marchesani syndrome.
Anjaiah Madugula et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 45(7), 769-770 (2006-07-13)
Determination of homatropine hydrobromide in eye drops by second-order derivative spectroscopy.
Leung C P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 9(2), 195-198 (1991)

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