Merck
CN

M4125

Sigma-Aldrich

D -甘露醇

≥98% (GC)

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别名:
甘露糖醇
Empirical Formula (Hill Notation):
C6H14O6
CAS号:
分子量:
182.17
Beilstein:
1721898
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.21

生物来源

plant

质量水平

检测方案

≥98% (GC)

形式

powder

颜色

white

useful pH range

5.0-6.5 (25 °C, 182 g/L, (77 °F ))

mp

167-170 °C (lit.)

溶解性

water: 100 mg/mL, clear, colorless

储存温度

room temp

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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此商品
17311M954663560
D-Mannitol ≥98% (GC)

Sigma-Aldrich

M4125

D -甘露醇

-
D-Mannitol tested according to Ph. Eur.

Sigma-Aldrich

17311

D -甘露醇

-
D-Mannitol BioXtra, ≥98% (HPLC)

Sigma-Aldrich

M9546

D -甘露醇

Premium Grade
D-Mannitol ACS reagent, suitable for microbiology, ≥99.0%

Millipore

63560

D -甘露醇

-
assay

≥98% (GC)

assay

≥97%

assay

≥98% (HPLC)

assay

≥99.0% (sum of enantiomers, HPLC)

form

powder

form

powder

form

powder

form

powder

color

white

color

-

color

white

color

-

useful pH range

5.0-6.5 (25 °C, 182 g/L, (77 °F ))

useful pH range

-

useful pH range

5.0-6.5 (25 °C, 182 g/L)

useful pH range

-

mp

167-170 °C (lit.)

mp

167-170 °C (lit.)

mp

167-170 °C (lit.)

mp

165-169 °C, 167-170 °C (lit.)

一般描述

D-甘露醇是一种天然存在的六碳糖醇或多元醇,存在于藻类、洋葱、草和橄榄等植物中。其血糖指数低于蔗糖,可视为安全。

应用

D-甘露醇已用于:
  • 渗透负荷,调节溶液的渗透压
  • 用作测试糖溶液的成分,用于纤维二糖-甘露醇渗透性测试
  • 用作核磁共振(NMR)内标,比较/分析尿液样本中的甘露醇浓度
  • 处理对照细胞并调节高糖渗透压

D-甘露醇已被用作羟基自由基清除剂和介质补充剂。

生化/生理作用

D-甘露醇可以增强AMP活化蛋白激酶(AMPK)和乙酰辅酶A羧化酶1 (ACC) 的磷酸化,可能在脂肪分解和脂肪氧化中具有重要作用。它用作减肥补充剂。D-甘露醇可刺激短链脂肪酸(SCFA)合成,从而调节肝脏中的脂质代谢。
一种糖醇类甜味剂。 用于甜味抑制研究。

其他说明

为了全面了解我们针对客户研究提供的各种糖醇产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)


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S J Upton et al.
Journal of clinical microbiology, 33(2), 371-375 (1995-02-01)
Surface-sterilized oocysts of Cryptosporidium parvum were applied to subconfluent monolayers of human adenocarcinoma (HCT-8) cells grown on coverslips in six-well cluster plates. Parasite-infected cultures were then incubated in RPMI 1640 with 10% fetal bovine serum, 15 mM HEPES (N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid)
A Matsuzaki et al.
Cancer research, 49(20), 5702-5707 (1989-10-15)
Rat 3Y1 fibroblasts transformed by the E1A gene of adenovirus type 12 (E1A-3Y1 cells) are highly sensitive to the cell-killing effect of 1,3-dilinoleoylglycerol (DLG) administered in a culture medium, whereas the parental 3Y1 cells are less sensitive (H. Shimura et
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
Pär Matsson et al.
Journal of medicinal chemistry, 48(2), 604-613 (2005-01-22)
The influence of different drug transport routes in intestinal drug permeability screening assays was studied. Three experimental models were compared: the small-intestine-like 2/4/A1 cell model, which has a leaky paracellular pathway, the Caco-2 cell model, which has a tighter paracellular

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