M9179
葡甲胺
99.0-100.5% dry basis, meets USP testing specifications
别名:
N -甲基- D -葡胺, 1-去氧-1-(甲胺)-D-山梨醇, 葡甲胺
生物来源
synthetic (organic)
质量水平
Agency
USP/NF
meets USP testing specifications
方案
99.0-100.5% dry basis
表单
powder
自燃温度
~662 °F
颜色
off-white
mp
129-131.5 °C (lit.)
溶解性
water: soluble
应用
pharmaceutical (small molecule)
储存温度
room temp
SMILES字符串
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
InChI key
MBBZMMPHUWSWHV-BDVNFPICSA-N
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应用
- 五价锑与 G-CSF 联合用于治疗由巴西利什曼病(Viannia)引起的皮肤利什曼病:研究发现,G-CSF结合葡甲胺有可能提升治疗效果(Suprien 等人,2024 年)。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Philipp Kickingereder et al.
Neuro-oncology, 17(8), 1139-1147 (2015-03-11)
To analyze the relevance of dynamic susceptibility-weighted contrast-enhanced MRI (DSC-MRI) derived relative cerebral blood volume (rCBV) analysis for predicting response to bevacizumab (BEV) in patients with recurrent glioblastoma (rGB). A total of 127 patients diagnosed with rGB receiving either bevacizumab
Raphaëlle Renard-Penna et al.
Radiology, 275(2), 458-468 (2015-01-20)
To compare the diagnostic performance of the magnetic resonance (MR) imaging-based Prostate Imaging Reporting and Data System (PI-RADS) and a Likert scale in the detection of prostate cancer in a cohort of patients undergoing initial prostate biopsy. This institutional review
Charlotte Manisty et al.
Radiology, 276(3), 732-740 (2015-04-30)
To investigate the pharmacology and potential clinical utility of splenic switch-off to identify understress in adenosine perfusion cardiac magnetic resonance (MR) imaging. Splenic switch-off was assessed in perfusion cardiac MR examinations from 100 patients (mean age, 62 years [age range
Andrea Barison et al.
Journal of cardiovascular medicine (Hagerstown, Md.), 16(10), 681-687 (2015-06-20)
In nonischaemic dilated cardiomyopathy (NICM), replacement myocardial fibrosis as detected by late gadolinium enhancement (LGE) at cardiovascular magnetic resonance (CMR) is associated with poor prognosis. We investigated the as-yet unexplored prognostic significance of interstitial fibrosis in NICM, using T1-mapping CMR.
Alexander Radbruch et al.
Radiology, 275(3), 783-791 (2015-04-08)
To compare changes in signal intensity (SI) ratios of the dentate nucleus (DN) and the globus pallidus (GP) to those of other structures on unenhanced T1-weighted magnetic resonance (MR) images between linear and macrocyclic gadolinium-based contrast agents (GBCAs). The study
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