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N2125

萘酚 AS-BI 磷酸盐

Name: 萘酚 AS-BI 磷酸盐
Brand: SIAL

≥98% purity (HPLC), powder

别名:

7-溴-3-羟基-2-萘-o-茴香醚磷酸盐

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关于此项目

经验公式（希尔记法）:

C₁₈H₁₅BrNO₆P

化学文摘社编号:

1919-91-1

分子量:

452.19

NACRES:

NA.47

PubChem Substance ID:

24897552

UNSPSC Code:

12171500

EC Number:

217-645-0

MDL number:

MFCD00004058

Beilstein/REAXYS Number:

6668526

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属性

产品名称

萘酚 AS-BI 磷酸盐, Technical grade, ≥98% (HPLC)

Quality Level

200

assay

≥98% (HPLC)

form

powder

technique(s)

microbe id | staining: suitable

color

white to light yellow

solubility

methanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

COc1ccccc1NC(=O)c2cc3cc(Br)ccc3cc2OP(O)(O)=O

InChI

1S/C18H15BrNO6P/c1-25-16-5-3-2-4-15(16)20-18(21)14-9-12-8-13(19)7-6-11(12)10-17(14)26-27(22,23)24/h2-10H,1H3,(H,20,21)(H2,22,23,24)

InChI key

HUXIAXQSTATULQ-UHFFFAOYSA-N

说明

General description

色酚AS-BI（也称为7-溴代-3- 羟基-2-萘酚-o-茴香胺）是一种取代萘酚。

酸性和碱性磷酸酶组织化学显示的底物。

Application

萘酚AS-BI磷酸可用于：

抗酒石酸酸性磷酸酶（TRAP）染色，以检测破骨细胞活性
Tris-HCl染色细胞的组成部分，以测定碱性磷酸酶（ALP）的活性
进行碱性磷酸酶反应

酸性和碱性磷酸酶组织化学显示的底物。酸性和碱性磷酸酶荧光测定法的底物。石蜡包埋组织中酸性磷酸酶的证明。单个活细胞中酸性磷酸酶的细胞荧光测定法。

Biochem/physiol Actions

色酚AS-BI可用作测定碱性和酸性磷酸酶的底物。也可用于测定单细胞酸性磷酸酶的活性。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A new method to localize acid phosphatase using the confocal laser-scanning microscope.

Z Szegedi et al.

Pathology oncology research : POR, 4(3), 217-223 (1998-10-08)

The aim of the study was to work out a technique for the detection of acid phosphatase enzyme activity by confocal laser-scanning microscope using the histochemical acid phosphatase detection method (after Barka and Anderson 1962, modified by Bowen and Lewis

Quantitative histochemical study of acid phosphatase activity in rat liver using a semipermeable membrane technique.

W M Frederiks et al.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 35(2), 175-180 (1987-02-01)

Acid phosphatase activity has been demonstrated in rat liver with the semipermeable membrane technique using naphthol AS-BI phosphate as substrate and hexazotized pararosaniline (HPRA) as simultaneous coupling agent. With this method the final reaction product (FRP) appeared in rat liver

Naphthol-ASBI phosphate as a preferred substrate for tartrate-resistant acid phosphatase isoform 5b.

A J Janckila et al.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 16(4), 788-793 (2001-04-24)

Tartrate-resistant acid phosphatase (TRAP) isoform 5b is a potential serum marker for osteoclastic activity. Biochemical assays for serum TRAP activity with para-nitrophenylphosphate (pNPP) have low specificity for bone because of hydrolysis by unrelated nontype 5 TRAPs of blood cells and

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全球贸易项目编号

货号	GTIN
N2125-1G	04061834110101
N2125-100MG	04061834110095
N2125-500MG	04061834110118
N2125-5G	04061832343686