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O1008

油酸

≥99% (GC)

别名:

9Z-十八碳烯酸，顺式-烯烃油酸, 顺式-9-十八碳烯酸, 反油酸

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关于此项目

线性分子式:
CH3(CH2)7CH=CH(CH2)7COOH
化学文摘社编号:
112-80-1
分子量:
282.46
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24278605
EC Number:
204-007-1
Beilstein/REAXYS Number:
1726542
MDL number:
MFCD00064242
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biological source

plant (Sunflower)

Quality Level

200

vapor pressure

1 mmHg ( 176 °C)

assay

≥99% (GC)

form

viscous liquid

color

colorless to very faintly yellow

refractive index

n20/D 1.459 (lit.)

bp

194-195 °C/1.2 mmHg (lit.)

mp

13-14 °C (lit.)

solubility

H2O: insoluble (practically), alcohol: soluble, benzene: soluble, chloroform: soluble, oil: soluble (fixed and volatile)

density

0.89 g/mL at 25 °C (lit.)

application(s)

life science and biopharma
lipidomics

functional group

oleic acid

lipid type

unsaturated FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI key

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

Gene Information

human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584), SOAT1(6646), SOAT2(8435)

General description

油酸 (OA) 是一种非必需脂肪酸，属于单不饱和脂肪酸 (MUFA)，橄榄油中富含这一成分。已有报道称，这种成分可从甘油三酯和偏甘油酯混合物中的定量去除。OA广泛用作稳定磁性纳米颗粒的表面活性剂。目前已制备出OA包覆的单分散磁铁矿纳米颗粒（7和19nm）。

Application

油酸可用于：
  • 研究脂肪酸对胃癌 (GC) 的影响
  • 诱导细胞培养物中的脂滴形成
  • 作为磁流变液制剂中的添加剂。
油酸可用于制备10-羟基十八烷酸和10-羟基十八烷酸甲酯。

Biochem/physiol Actions

众所周知，油酸可以改善免疫功能和健康。膳食补充这种脂肪酸有助于降低胆固醇水平、动脉粥样硬化风险、血压及宿主对移植物的反应。油酸经证有抗炎作用，有助对抗自身免疫性疾病。它还可以改善乳腺癌状况。油酸可引起多种生理效应，如肝细胞中的蛋白激酶C活化、氧化磷酸化解偶联及2,4-二硝基苯酚−刺激的 ATP 酶抑制。通过添加血清白蛋白可以逆转这种作用。

Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

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存储类别

10 - Combustible liquids

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000527720
0000522140
0000525569
0000525568
0000525568

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实验方案

Protocol for In-vitro Permeation Testing Using Strat-M® Membranes

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

商品

DISCOVER Bioactive Small Molecules for Neuroscience

DISCOVER Bioactive Small Molecules for Neuroscience

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

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THE STEREOSPECIFIC CONVERSION OF STEARIC ACID TO OLEIC ACID.
G J SCHROEPFER et al.
The Journal of biological chemistry, 240, 54-63 (1965-01-01)
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Pan J, et al.
Journal of Experimental & Clinical Cancer Research, 38 (2019)
Kun Huang et al.
Journal of hepatology, 66(5), 962-977 (2016-12-17)
PARP1 is a key mediator of cellular stress responses and critical in multiple physiological and pathophysiological processes of cells. However, whether it is involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) remains elusive. We analysed PARP1 activity in
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全球贸易项目编号

货号GTIN
O1008-25G04061835507085
O1008-5G04061835547142
O1008-1G04061835547135