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经验公式(希尔记法):
C32H32N2O12
化学文摘社编号:
分子量:
636.60
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
219-318-8
Beilstein/REAXYS Number:
381994
MDL number:
产品名称
邻甲酚酞络合酮, powder
InChI key
IYZPEGVSBUNMBE-UHFFFAOYSA-N
InChI
1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)
SMILES string
Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4
form
powder
technique(s)
titration: suitable
color
white to off-white
mp
181-185 °C (dec.) (lit.)
solubility
methanol: 1 mg/mL
suitability
suitable for determination of calcium
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
邻甲酚酞络合酮的应用包括,通过Ca2+和邻甲酚酞络合酮在碱性溶液中的反应检测血清样本中的钙含量。
General description
邻甲酚酞络合酮(o-Cresolphthalein Complexone)是一种pH指示剂和(金属络合指示剂),常用于通过量热法检测血清中的钙含量。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J Toffaletti et al.
Clinical chemistry, 26(11), 1562-1565 (1980-10-01)
We adapted a method for dialyzable calcium from fluorometric detection by use of calcein to a more specific spectrophotometric determination with cresolphthalein complexone. The reagents are available commercially and perform satisfactorily with respect to noise level, drift, stability, and sensitivity.
Improved determination of serum calcium with 2-cresolphthalein complexone.
K Lorentz
Clinica chimica acta; international journal of clinical chemistry, 126(3), 327-334 (1982-12-23)
Improved linearity of the calcium-cresolphthalein complexone reaction with sodium acetate.
D M Cowley et al.
Clinical chemistry, 32(5), 894-895 (1986-05-01)
C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
C M Corns
Annals of clinical biochemistry, 27 ( Pt 2), 152-155 (1990-03-01)
The spectral interference caused by haemoglobin in the calcium-cresolphthalein complexone reaction was investigated. The results show that the nature of the haemoglobin derivative in the reaction mixture influences the degree of interference; in turn, the derivative formed depends on the
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