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Merck
CN

P5631

Sigma-Aldrich

邻甲酚酞络合酮

powder

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别名:
二甲苯酞-双亚氨基二乙酸, 邻甲酚酞-3′,3′′-双甲基亚氨基二乙酸, 邻甲酚酞络合剂, 酞紫, 金属酞
经验公式(希尔记法):
C32H32N2O12
CAS号:
分子量:
636.60
Beilstein:
381994
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

形式

powder

质量水平

颜色

white to off-white

mp

181-185 °C (dec.) (lit.)

溶解性

methanol: 1 mg/mL

适用性

suitable for determination of calcium

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4

InChI

1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

InChI key

IYZPEGVSBUNMBE-UHFFFAOYSA-N

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一般描述

邻甲酚酞络合酮(o-Cresolphthalein Complexone)是一种pH指示剂和(金属络合指示剂),常用于通过量热法检测血清中的钙含量。

应用

邻甲酚酞络合酮的应用包括,通过Ca2+和邻甲酚酞络合酮在碱性溶液中的反应检测血清样本中的钙含量。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
M A Koupparis et al.
Clinical chemistry, 28(10), 2149-2152 (1982-10-01)
We describe the measurement of total calcium and magnesium in serum with an automated microcomputer-controlled stopped-flow analyzer. The calcium method is based on the cresolphthalein complexone procedure, with 2-amino-3-methyl-1-propanol as the alkalinizing agent. The assay, performed on 60-fold prediluted samples
R J Liedtke et al.
Clinical chemistry, 27(12), 2025-2028 (1981-12-01)
We describe an automated method for calcium assay, for use with the Cobas-Bio centrifugal analyzer. Calcium is reacted with cresolphthalein complexone and the absorbance of the calcium--dye complex at 575 nm is measured. EDTA is then added to break up
Sandra F Williams et al.
Mayo Clinic proceedings, 80(12), 1655-1657 (2005-12-14)
Severe hypocalcemia may require prompt intervention to avoid life-threatening consequences. We report a case in which a 78-year-old man had a critically low serum calcium level measured with use of standard colorimetric assay after gadodiamide administration during magnetic resonance angiography.
A E Hartmann et al.
American journal of clinical pathology, 82(2), 182-187 (1984-08-01)
An automated calcium method based on o-cresolphthalein complexone chemistry and designed to be used in conjunction with the Beckman ASTRA systems (Beckman Instruments, Inc., Brea, CA) was evaluated. Day-to-day reproducibility studies yielded coefficients of variation ranging from 1.2 to 3.1%.

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