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Merck
CN

PHR1020

Supelco

甘油

greener alternative

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

甘油, 1,2,3-丙三醇

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关于此项目

线性分子式:
HOCH2CH(OH)CH2OH
化学文摘社编号:
分子量:
92.09
Beilstein:
635685
EC 号:
MDL编号:
UNSPSC代码:
12161500
PubChem化学物质编号:
NACRES:
NA.24
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等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. G0400000
traceable to USP 1295607

蒸汽密度

3.1 (vs air)

蒸汽压

<1 mmHg ( 20 °C)

API类

glycerin

CofA

current certificate can be downloaded

自燃温度

698 °F

环保替代产品特性

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

技术

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.474 (lit.)

沸点

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

密度

1.25 g/mL (lit.)

应用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

包装形式

neat

环保替代产品分类

储存温度

2-30°C

SMILES字符串

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

应用

甘油可作为药物参考标准品,用于通过色谱技术测定药物制剂和化妆品中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。

分析说明

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

其他说明

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析(使用数字化外标)。可查看该物质的NMR谱图,只需点击几次鼠标,就能进行在线样品比对。欢迎点击了解更多,开启免费试用之旅。
要查看该材料的分析证书示例,请在下面的栏位中输入 LRAB7812。这只是一个示例证书,可能不是您收到的批次。
该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

390.2 °F - Pensky-Martens closed cup

闪点(°C)

199 °C - Pensky-Martens closed cup


分析证书(COA)

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Stability indicating HPTLC determination of timolol maleate as bulk drug and in pharmaceutical preparations
Kulkarni SP and Amin PD
Journal of Pharmaceutical and Biomedical Analysis, 23(6), 983-987 (2000)
E Mikami et al.
Journal of pharmaceutical and biomedical analysis, 28(2), 261-267 (2002-04-04)
A high-performance liquid chromatographic (HPLC) method for simultaneous determination of dehydroacetic acid (DHA), benzoic acid (BA), sorbic acid (SOA) and salicylic acid (SA) was developed for application to cosmetic products. Isocratic reversed-phase HPLC was employed for quantitative analysis using tetra-n-butylammonium
Hovsep Mahdessian et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8913-8918 (2014-06-14)
Genome-wide association studies have identified a locus on chromosome 19 associated with plasma triglyceride (TG) concentration and nonalcoholic fatty liver disease. However, the identity and functional role of the gene(s) responsible for these associations remain unknown. Of 19 expressed genes
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
Tian Qiu et al.
Nature communications, 5, 5119-5119 (2014-11-05)
Biological microorganisms swim with flagella and cilia that execute nonreciprocal motions for low Reynolds number (Re) propulsion in viscous fluids. This symmetry requirement is a consequence of Purcell's scallop theorem, which complicates the actuation scheme needed by microswimmers. However, most

实验方案

99%;甘油,≥99.5%;四甘醇,99%

Chromatograms

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