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Merck
CN

PHR1073

阿伏苯宗 CRM

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

丁基甲氧基二苯甲酰甲烷, 阿伏苯宗

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关于此项目

经验公式(希尔记法):
C20H22O3
化学文摘社编号:
分子量:
310.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
274-581-6
MDL number:
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产品名称

阿伏苯宗 CRM, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

XNEFYCZVKIDDMS-UHFFFAOYSA-N

InChI

1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3

SMILES string

COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1045337

API family

avobenzone

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Application

这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
阿伏苯宗可用作药物参考标准品,用于通过高效液相色谱技术对药物制剂中的分析物进行定量。

General description

阿伏苯宗是一种防晒霜活性成分,用于防晒露和化妆品配方。
用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Other Notes

要查看该材料的分析证书示例,请在下面的栏位中输入 LRAB3693。这只是一个示例证书,可能不是您收到的批次。
该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 2


分析证书(COA)

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Development and validation of a new RP-HPLC method for the simultaneous determination of hydroquinone, kojic acid, octinoxate, avobenzone, BHA and BHT in skin-whitening cream.
Galimany-Rovira F, et al.
Analytical Methods : Advancing Methods and Applications, 8(5), 1170-1180 (2016)
Jing Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 605-612 (2008-01-30)
The objective of the present study was to determine the effects of hydroxypropyl-beta-cyclodextrin (HPCD) complexation on the transdermal penetration and photostability of a model ultraviolet A (UVA) absorber, butyl methoxydibenzoylmethane (avobenzone), and to determine the influence of complexation on in
Virginie Lhiaubet-Vallet et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(4), 552-558 (2010-04-01)
In most sunscreens, the presence of two UV filters usually leads to synergistic effects regarding both the final performance and photostabilization of the active principles. However, this may also result in an accelerated decomposition if a photoreaction occurs between the
Daniele Dondi et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 5(9), 835-843 (2006-10-19)
A systematic investigation of two well-known and popular commercial suncreams reveals significant degradation when exposed to simulated UV sunlight at an irradiance corresponding to natural sunlight. We have examined the photochemistry of two widely used sunscreen active agents in pure
Robert M Sayre et al.
Photochemistry and photobiology, 81(2), 452-456 (2004-11-25)
A major concern raised about photostability studies of sunscreen products is that the photodegradation of sunscreens does not readily translate into changes in product performance. This study examines the correlation between photochemical degradation of sunscreen agents and changes in protection

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